Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17177622 | 0.79 | MAOA (0.37) | MAOAMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL15290758 | 0.74 | ALDH1A1 (0.32) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL16627767 | 0.74 | MEN1 (0.38) | TDP1ALDH1A1MAPK1CES2CES1 | |
| SCHEMBL21745877 | 0.73 | MAOA (0.33) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL15290752 | 0.72 | MAOA (0.33) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL20037284 | 0.69 | KDM1A (0.42) | TDP1ALDH1A1MAPK1CES2CES1 | |
| SCHEMBL18376077 | 0.68 | CES1 (0.35) | MAOAMAOBTDP1ALDH1A1MAPK1 | |
| SCHEMBL17518762 | 0.68 | ATM (0.33) | MAOAMAOBCES2CES1MEN1 | |
| SCHEMBL1637841 | 0.66 | MTNR1A (0.42) | TDP1ALDH1A1MAPK1CES2CES1 | |
| SCHEMBL8331470 | 0.66 | NFE2L2 (0.43) | TDP1ALDH1A1MAPK1CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170012223-A1 | Organic Electroluminescent Materials and Devices | UNIVERSAL DISPLAY CORPORATION | 2017-01-12 | — | — | US | disclosed |
| US-20160093816-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-31 | — | — | US | disclosed |
| US-20150295187-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2015-10-15 | — | — | US | disclosed |
| US-20150097169-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-09 | — | — | US | disclosed |
| US-20150090981-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170012223-A1 | Organic Electroluminescent Materials and Devices | EML4, MT-ND4L, MT-ND4 | MAOA 1566/4885MAOB 1968/4885TDP1 4523/4885 |
| US-20150295187-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | MLX, LOXL4, LOXL1 | MAOA 533/4885MAOB 275/4885TDP1 3939/4885 |
| US-20160093816-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | ACSL3, LUC7L2, L3MBTL3 | MAOA 840/4885MAOB 444/4885TDP1 3984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.