Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | MAOB | P27338 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17177624 | 0.79 | MAOA (0.37) | ALDH1A1SMN1; SMN2MAOAMAOBKDM4E | |
| SCHEMBL15290744 | 0.74 | ACMSD (0.31) | KDM4E | |
| SCHEMBL15290752 | 0.72 | MAOA (0.33) | NPSR1ALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL15290756 | 0.72 | MEN1 (0.33) | NPC1RAB9ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL19936387 | 0.69 | TDP1 (0.40) | NPSR1ALDH1A1MAOAMAOBTDP1 | |
| SCHEMBL21745877 | 0.69 | MAOA (0.33) | NPSR1ALDH1A1SMN1; SMN2MAOAMAOB | |
| SCHEMBL14141387 | 0.68 | PKM (0.38) | NPC1RAB9ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4756877 | 0.68 | NPC1 (0.63) | NPC1RAB9ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6308174 | 0.68 | NPC1 (0.63) | NPC1RAB9ANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7739379 | 0.68 | NPC1 (0.63) | NPC1RAB9ANPSR1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160049599-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2016-02-18 | — | — | US | disclosed |
| US-20150315222-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2015-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160049599-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | SRSF6, SRSF1, DBF4 | NPC1 3849/4885RAB9A 1930/4885NPSR1 616/4885 |
| US-20150315222-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | MLX, SSB, RPS4X | NPC1 4462/4885RAB9A 842/4885NPSR1 996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.