Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13874287 | 0.84 | ALDH1A1 (0.42) | MAPTLMNAKMT2AMEN1HIF1A | |
| SCHEMBL14141387 | 0.82 | PKM (0.38) | MAPTLMNAKMT2AHSD17B10MEN1 | |
| SCHEMBL21746252 | 0.79 | PRSS1 (0.48) | MAPTKMT2AMEN1CYP3A4CA1 | |
| SCHEMBL19443447 | 0.78 | LOXL2 (0.48) | ABAT | |
| SCHEMBL14204477 | 0.78 | MAPT (0.42) | MAPTLMNAKMT2AHSD17B10MEN1 | |
| SCHEMBL18871578 | 0.77 | ESR1 (0.39) | ESR1MAPTKMT2AHSD17B10MEN1 | |
| SCHEMBL21746584 | 0.75 | HDAC3 (0.42) | ALDH1A1TSHR | |
| SCHEMBL18831458 | 0.75 | HSP90AA1 (0.40) | MAPTLMNAKMT2AHSD17B10MEN1 | |
| SCHEMBL17267202 | 0.74 | HDAC1 (0.46) | MAPTLMNAKMT2AMEN1CYP1A2 | |
| SCHEMBL21746596 | 0.74 | ELANE (0.47) | ESR1MAPTLMNAKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |