Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21746252 | 0.80 | PRSS1 (0.48) | KMT2AMEN1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL13874287 | 0.74 | ALDH1A1 (0.42) | KMT2AMEN1LMNAMAPTALDH1A1 | |
| SCHEMBL21746470 | 0.74 | ESR1 (0.40) | HSD17B10KMT2AMEN1LMNAESR1 | |
| SCHEMBL21746471 | 0.74 | NR1I2 (0.49) | CHRM2SLC6A2SLC6A3MAPTALDH1A1 | |
| SCHEMBL21746634 | 0.73 | ELANE (0.45) | ELANEHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL14141387 | 0.72 | PKM (0.38) | HSD17B10KMT2AMEN1LMNAMAPT | |
| SCHEMBL9339013 | 0.71 | ELANE (0.83) | ELANEHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL27500022 | 0.71 | PRSS1 (0.59) | ELANEHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL269329 | 0.71 | LMNA (0.80) | ELANEHSD17B10KMT2AMEN1LMNA | |
| SCHEMBL9302775 | 0.70 | ELANE (0.62) | ELANEHSD17B10KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |