Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4092385 | 0.98 | L3MBTL1 (0.54) | NPSR1L3MBTL1ALDH1A1CHKALMNA | |
| SCHEMBL28119608 | 0.91 | NPSR1 (0.49) | NPSR1L3MBTL1ALDH1A1CHKALMNA | |
| SCHEMBL127407 | 0.85 | ALDH1A1 (0.52) | NPSR1L3MBTL1ALDH1A1CHKALMNA | |
| Bromide SCHEMBL140800 | 0.84 | LMNA (0.55) | NPSR1L3MBTL1ALDH1A1CHKALMNA | |
| SCHEMBL736568 | 0.81 | LMNA (0.56) | NPSR1L3MBTL1ALDH1A1CHKALMNA | |
| SCHEMBL10626173 | 0.81 | CA2 (0.52) | NPSR1L3MBTL1ALDH1A1CHKALMNA | |
| SCHEMBL21750919 | 0.80 | NPSR1 (0.40) | NPSR1L3MBTL1ALDH1A1CHKALMNA | |
| Hydrochloric Acid SCHEMBL34474399 | 0.80 | L3MBTL1 (0.64) | NPSR1L3MBTL1ALDH1A1CHKALMNA | |
| Iodide SCHEMBL8728732 | 0.80 | L3MBTL1 (0.69) | NPSR1L3MBTL1ALDH1A1CHKALMNA | |
| Hydrochloric Acid SCHEMBL11604013 | 0.79 | MAPT (0.54) | NPSR1L3MBTL1ALDH1A1CHKALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062783-A1 | PHOTO LEWIS ACID GENERATOR | NIPPON SHOKUBAI CO., LTD. (JP) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062783-A1 | PHOTO LEWIS ACID GENERATOR | LEO1, LRRK2, LSG1 | CHKA 3715/4885NPSR1 2746/4885L3MBTL1 121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.