SCHEMBL21751213

SCHEMBL21751213

CCCC[Sn](CCCC)(CCCC)c1cc(C)c(-c2sc(-c3sccc3C)c(C#N)c2C#N)s1

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
MEN1 O00255 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21751223 0.79 KDM4E (0.34) ALDH1A1KDM4ELMNA
SCHEMBL21751219 0.76 CYP2A6 (0.40) ALDH1A1KDM4ELMNAMEN1MAPT
SCHEMBL21751212 0.74 KDM4E (0.33) ALDH1A1KDM4ELMNA
SCHEMBL4148284 0.66 KDM4E (0.31) ALDH1A1KDM4EMEN1MAPTKMT2A
SCHEMBL3421058 0.65 TRPM8 (0.32)
SCHEMBL30973811 0.65
SCHEMBL1764784 0.65 MEN1 (0.30) ALDH1A1MEN1MAPTKMT2A
SCHEMBL27965804 0.65
SCHEMBL13505901 0.64 GPR35 (0.35) ALDH1A1
SCHEMBL22654108 0.63 HDAC3 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435100-B2 Perovskite solar cells PURDUE RESEARCH FOUNDATION (US) 2025-10-07 US disclosed
US-11800784-B2 Two-dimensional halide perovskite materials PURDUE RESEARCH FOUNDATION (US) 2023-10-24 US disclosed
US-20220246865-A1 PEROVSKITE SOLAR CELLS PURDUE RESEARCH FOUNDATION (US) 2022-08-04 US disclosed
US-20210343948-A1 Two-Dimensional Halide Perovskite Materials PURDUE RESEARCH FOUNDATION (US) 2021-11-04 US disclosed
US-10618889-B2 Thiophene monoamine based organic-inorganic hybrid perovskites PURDUE RESEARCH FOUNDATION (US) 2020-04-14 US disclosed
US-20200062740-A1 THIOPHENE MONOAMINE BASED ORGANIC-INORGANIC HYBRID PEROVSKITES PURDUE RESEARCH FOUNDATION (US) 2020-02-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10618889-B2 Thiophene monoamine based organic-inorganic hybrid perovskites COMT, TYR, SLC6A3 ALDH1A1 751/4885KDM4E 385/4885LMNA 4797/4885
US-20210343948-A1 Two-Dimensional Halide Perovskite Materials EYA2, BRAP, EYA3 ALDH1A1 2678/4885KDM4E 1729/4885LMNA 2838/4885
US-20220246865-A1 PEROVSKITE SOLAR CELLS BCL3, MCL1, ANXA3 ALDH1A1 2526/4885KDM4E 2467/4885LMNA 1735/4885
US-12435100-B2 Perovskite solar cells BCL3, MCL1, ANXA3 ALDH1A1 2526/4885KDM4E 2467/4885LMNA 1735/4885
US-11800784-B2 Two-dimensional halide perovskite materials EYA2, BRAP, EYA3 ALDH1A1 2678/4885KDM4E 1729/4885LMNA 2838/4885
US-20200062740-A1 THIOPHENE MONOAMINE BASED ORGANIC-INORGANIC HYBRID PEROVSKITES COMT, TYR, SLC6A3 ALDH1A1 751/4885KDM4E 385/4885LMNA 4797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.