Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 7/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29634416 | 1.00 | DRD2 (0.36) | DRD2DRD4ESR1ESR2HSD17B10 | |
| SCHEMBL3755892 | 0.90 | ESR1 (0.38) | DRD2DRD4ESR1ESR2HSD17B10 | |
| SCHEMBL9995642 | 0.85 | DRD2 (0.35) | DRD2DRD4ESR1ESR2HSD17B10 | |
| SCHEMBL28861019 | 0.84 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL275808 | 0.82 | PBRM1 (0.36) | DRD2DRD4ESR1ESR2HSD17B10 | |
| SCHEMBL1476906 | 0.78 | DRD2 (0.38) | DRD2DRD4ESR1ESR2HSD17B10 | |
| SCHEMBL3861910 | 0.78 | DRD2 (0.36) | DRD2DRD4ESR1ESR2HSD17B10 | |
| SCHEMBL1896564 | 0.77 | HTR2C (0.38) | DRD4 | |
| SCHEMBL31513977 | 0.77 | HTR2C (0.38) | DRD4 | |
| Indene SCHEMBL16297370 | 0.76 | CA1 (0.47) | ESR1ESR2HSD17B10CA2CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 208 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127694-A1 | FRAGRANCE COMPOSITIONS AND USES THEREOF | COTY INC. | 2025-04-24 | — | — | US | disclosed |
| CN-114127038-B | Isomerization process for products obtained from the condensation reaction of ketones and phenols to bisphenols | PTT全球化学公共有限公司 | 2025-01-03 | — | — | CN | disclosed |
| US-12037346-B2 | Amino-substituted heteroaryls for treating cancers with EGFR mutations | NUVALENT, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-20230159766-A1 | CONDUCTIVE POLYMER COMPOSITION, SUBSTRATE, AND METHOD FOR PRODUCING SUBSTRATE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-05-25 | — | — | US | disclosed |
| CN-106232794-B | Fabric care compositions comprising polyurethane, polyurea and/or polyurethaneurea polymers | 宝洁公司 | 2023-04-21 | — | — | CN | disclosed |
| US-11573491-B2 | Negative tone photosensitive composition for EUV light, pattern forming method, and method for manufacturing electronic device | FUJIFILM CORPORATION (JP) | 2023-02-07 | — | — | US | disclosed |
| CN-114127038-A | Process for isomerizing products obtained from the condensation of ketones and phenols to produce bisphenols | PTT全球化学公共有限公司 | 2022-03-01 | — | — | CN | disclosed |
| US-20210011380-A1 | NEGATIVE TONE PHOTOSENSITIVE COMPOSITION FOR EUV LIGHT, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE | FUJIFILM CORPORATION (JP) | 2021-01-14 | — | — | US | disclosed |
| CN-112105654-A | Curable resin mixture, curable resin composition, and cured product thereof | 日本化药株式会社 | 2020-12-18 | — | — | CN | disclosed |
| US-20200259094-A1 | CONDUCTIVE POLYMER COMPOSITE AND CONDUCTIVE POLYMER COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-08-13 | — | — | US | disclosed |
| WO-2006062240-A1 | 3-ETHYLIDENEHYDRAZINO SUBSTITUTED HETEROCYCLIC COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2006-06-15 | — | — | WO | disclosed |
| US-20060094694-A1 | Heterocyclic compounds and thrombopoietin receptor activators | NISSAN CHEMICAL INDUSTRIES LIMITED (JP) | 2006-05-04 | — | — | US | disclosed |
| EP-1636192-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| US-20060014106-A1 | Photoresist undercoat-forming material and patterning process | SHIN-ETSU CHEMICAL CO., LTD. | 2006-01-19 | — | — | US | disclosed |
| WO-2004108683-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
| US-4806555-A | CARDIAC ARRHYTHMIA INHIBITOR | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-02-21 | — | — | US | disclosed |
| US-4609735-A | HYPOTENSIVE, ANTIARRHYTHMIA | A. H. ROBINS COMPANY, INC. (US) | 1986-09-02 | — | — | US | disclosed |
| US-4538001-A | FROM 1-ARYLOXY-4-CHLORO-2-BUTANOL INTERMEDIATES; LOCAL ANESTHETICS, ANTIARRHYTHMICS, HYPOTENSIVES, BETA-ADRENERGIC BLOCKERS | A. H. ROBINS COMPANY, INC. (US) | 1985-08-27 | — | — | US | disclosed |
| US-4463190-A | FOR USE AS ADRENERGIC BLOCKING, HYPOTENSIVE, AND HYPOTENSIVE AGENTS; LOCAL ANESTHETIC | A. H. ROBINS COMPANY, INC. (US) | 1984-07-31 | — | — | US | disclosed |
| US-4379167-A | 1-Aryloxy-4-amino-2-butanols and the pharmaceutical use thereof | A. H. ROBINS COMPANY, INC. (US) | 1983-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037346-B2 | Amino-substituted heteroaryls for treating cancers with EGFR mutations | EGFR, ERBB2, ERBB3 | DRD2 4326/4885DRD4 4369/4885ESR1 306/4885 |
| US-20060094694-A1 | Heterocyclic compounds and thrombopoietin receptor activators | NR2C2, ROR1, NR0B2 | DRD2 1694/4885DRD4 1903/4885ESR1 96/4885 |
| US-20250127694-A1 | FRAGRANCE COMPOSITIONS AND USES THEREOF | TRPA1, TRPV1, NAA40 | DRD2 2569/4885DRD4 2954/4885ESR1 3601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.