Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.38 |
| ▸ | DRD4 | P21917 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | DRD1 | P21728 | 4/20 | 0.36 |
| ▸ | DRD5 | P21918 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9995737 | 0.88 | MAOA (0.42) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL8509475 | 0.83 | PBRM1 (0.38) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL27861267 | 0.79 | HTR2C (0.39) | — | |
| SCHEMBL7472008 | 0.78 | DRD2 (0.41) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL29634416 | 0.78 | DRD2 (0.36) | DRD2DRD4DRD3DRD1DRD5 | |
| SCHEMBL217518 | 0.78 | DRD2 (0.36) | DRD2DRD4DRD3DRD1DRD5 | |
| Hydroquinone SCHEMBL28586906 | 0.76 | CYP1A2 (0.39) | MAOBHSD17B10HSP90AA1ESR1ESR2 | |
| SCHEMBL13448121 | 0.75 | — | — | |
| SCHEMBL13523394 | 0.75 | ADRA2A (0.37) | — | |
| SCHEMBL17544729 | 0.75 | CASP1 (0.38) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013083582-A1 | ANTIMICROBIAL COMPOSITION | UNILEVER N.V. (NL) | 2013-06-13 | — | — | WO | claimed |
| CN-117813306-A | Heterocyclic compounds as KRAS inhibitors, their preparation and therapeutic use | 上海科州药物研发有限公司 | 2024-04-02 | — | — | CN | disclosed |
| WO-2022247760-A1 | HETEROCYCLIC COMPOUNDS AS KRAS INHIBITOR, AND PREPARATION THEREFOR AND USE THEREOF IN TREATMENT | 上海科州药物研发有限公司 | 2022-12-01 | — | — | WO | disclosed |
| CN-109963848-B | Substituted N- (3-fluoropropyl) -pyrrolidine compounds, preparation thereof and therapeutic use thereof | 赛诺菲 | 2022-07-05 | — | — | CN | disclosed |
| CN-106661009-B | Anti- enteric virus71 thiadiazolidine derivative | 江苏康缘药业股份有限公司 | 2019-11-26 | — | — | CN | disclosed |
| CN-105085436-B | Sulfonic acid amide derivatives and its application on drug | 广东东阳光药业有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-105705489-B | Compound as immunomodulator | 百时美施贵宝公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-109320517-A | FXR receptor stimulating agent | 海南轩竹医药科技有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-108602811-A | FXR receptor stimulating agents | 山东轩竹医药科技有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108349952-A | Tetrahydronaphthalene estrogen receptor modulators and uses thereof | 豪夫迈·罗氏有限公司 | 2018-07-31 | — | — | CN | disclosed |
| WO-2001094452-A2 | UV CURABLE COATING FOR GOLF BALLS | LORD CORPORATION (US) | 2001-12-13 | — | — | WO | disclosed |
| WO-2001068654-A2 | TUBULIN BINDING LIGANDS AND CORRESPONDING PRODRUG CONSTRUCTS | BAYLOR UNIVERSITY (US) | 2001-09-20 | — | — | WO | disclosed |
| EP-1044181-A1 | BENZYL AND BENZYLIDENE TETRALINS AND DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999035115-A1 | BENZYL AND BENZYLIDENE TETRALINS AND DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 1999-07-15 | — | — | WO | disclosed |
| WO-1999007360-A1 | COMPOUNDS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |
| US-4400543-A | ANTIFERTILITY AGENTS | ELI LILLY AND COMPANY (US) | 1983-08-23 | — | — | US | disclosed |
| US-4323707-A | USEFUL FOR AMIMALS, AROYL-PHENYL-NAPHTHALENES OR DIHYDRONAPHTHALENES | ELI LILLY AND COMPANY (US) | 1982-04-06 | — | — | US | disclosed |
| US-4230862-A | 3-PHENYL-4-AROYL-1,2-DIHYDRONAPHTHALENES AND 1-ARYOYL-2-PHENYLNAPHTHALENES | ELI LILLY AND COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| US-4075223-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |
| US-4017546-A | AROYL PHENYL INDENES AND AROYL PHENYL NAPHTHALENES | ELI LILLY AND COMPANY (US) | 1977-04-12 | — | — | US | disclosed |