SCHEMBL21752956

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21628491	0.86	HIF1A (0.49)	MEN1KMT2ARAB9ALMNAHIF1A
	SCHEMBL21752960	0.85	MEN1 (0.50)	MEN1KMT2ARAB9ALMNAHIF1A
	SCHEMBL20827018	0.85	MEN1 (0.54)	MEN1KMT2ARAB9ALMNAHIF1A
	SCHEMBL21628411	0.83	HDAC6 (0.47)	MEN1KMT2ARAB9AHIF1AEPAS1
	SCHEMBL20482054	0.83	HIF1A (0.54)	MEN1KMT2ARAB9ALMNAHIF1A
	SCHEMBL21628483	0.82	MEN1 (0.45)	MEN1KMT2ARAB9ALMNAHIF1A
	SCHEMBL21628643	0.82	OPRM1 (0.49)	MEN1KMT2ARAB9ALMNAHIF1A
	SCHEMBL21656984	0.80	PDE4B (0.53)	MEN1KMT2ARAB9ALMNAHIF1A
	SCHEMBL19638786	0.75	ALDH1A1 (0.57)	MEN1KMT2ARAB9ALMNAHIF1A
	SCHEMBL31225326	0.75	ALDH1A1 (0.57)	MEN1KMT2ARAB9ALMNAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.