Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 10/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | MDH1 | P40925 | 1/20 | 0.41 |
| ▸ | MDH2 | P40926 | 1/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | RARA | P10276 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20827018 | 0.89 | MEN1 (0.54) | HIF1AEPAS1MEN1KMT2ARAB9A | |
| SCHEMBL20482054 | 0.87 | HIF1A (0.54) | HIF1AEPAS1MEN1KMT2ARAB9A | |
| SCHEMBL21628411 | 0.87 | HDAC6 (0.47) | HIF1AEPAS1MEN1KMT2ARAB9A | |
| SCHEMBL21628643 | 0.86 | OPRM1 (0.49) | HIF1AEPAS1MEN1KMT2ARAB9A | |
| SCHEMBL21628483 | 0.86 | MEN1 (0.45) | HIF1AEPAS1MEN1KMT2ARAB9A | |
| SCHEMBL21752956 | 0.86 | MEN1 (0.45) | HIF1AEPAS1MEN1KMT2ARAB9A | |
| SCHEMBL21656984 | 0.84 | PDE4B (0.53) | HIF1AEPAS1MEN1KMT2ARAB9A | |
| SCHEMBL19362904 | 0.84 | MEN1 (0.55) | HIF1AEPAS1MEN1KMT2ARAB9A | |
| SCHEMBL19638786 | 0.79 | ALDH1A1 (0.57) | HIF1AMEN1KMT2ARAB9AMAPT | |
| SCHEMBL31225326 | 0.79 | ALDH1A1 (0.57) | HIF1AMEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12600696-B2 | Aromatic compounds | Xeniopro GmbH (DE) | 2026-04-14 | — | — | US | disclosed |
| US-20230406814-A2 | NOVEL AROMATIC COMPOUNDS | Xeniopro GmbH (DE) | 2023-12-21 | — | — | US | disclosed |
| US-20230150923-A1 | NOVEL AROMATIC COMPOUNDS | Xeniopro GmbH (DE) | 2023-05-18 | — | — | US | disclosed |
| US-11591289-B2 | Aromatic compounds | Xeniopro GmbH (DE) | 2023-02-28 | — | — | US | disclosed |
| US-20220348535-A2 | NOVEL AROMATIC COMPOUNDS | Xeniopro GmbH (DE) | 2022-11-03 | — | — | US | disclosed |
| US-20210107863-A2 | NOVEL AROMATIC COMPOUNDS | Xeniopro GmbH (DE) | 2021-04-15 | — | — | US | disclosed |
| US-20210107863-A2 | NOVEL AROMATIC COMPOUNDS | Xeniopro GmbH (DE) | 2021-04-15 | — | — | US | disclosed |
| US-10772876-B2 | Enhancers of Notch signaling and the use thereof in the treatment of cancers and malignancies medicable by upregulation of Notch | Xeniopro GmbH (DE) | 2020-09-15 | — | — | US | disclosed |
| US-20200031763-A1 | NOVEL AROMATIC COMPOUNDS | Xeniopro GmbH (DE) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10772876-B2 | Enhancers of Notch signaling and the use thereof in the treatment of cancers and malignancies medicable by upregulation of Notch | NOTCH1, DNER, NOTCH4 | HIF1A 2685/4885EPAS1 805/4885MEN1 23/4885 |
| US-20230150923-A1 | NOVEL AROMATIC COMPOUNDS | AHR, TYR, MUSK | HIF1A 2000/4885EPAS1 870/4885MEN1 4341/4885 |
| US-20220348535-A2 | NOVEL AROMATIC COMPOUNDS | AHR, TYR, MUSK | HIF1A 2000/4885EPAS1 870/4885MEN1 4341/4885 |
| US-11591289-B2 | Aromatic compounds | AHR, TYR, MUSK | HIF1A 1618/4885EPAS1 982/4885MEN1 4012/4885 |
| US-20210107863-A2 | NOVEL AROMATIC COMPOUNDS | AHR, TYR, MUSK | HIF1A 2000/4885EPAS1 870/4885MEN1 4341/4885 |
| US-12600696-B2 | Aromatic compounds | CCR1, CCRL2, AHR | HIF1A 1180/4885EPAS1 2034/4885MEN1 3190/4885 |
| US-20230406814-A2 | NOVEL AROMATIC COMPOUNDS | AHR, TYR, MUSK | HIF1A 2000/4885EPAS1 870/4885MEN1 4341/4885 |
| US-20200031763-A1 | NOVEL AROMATIC COMPOUNDS | AHR, TYR, MUSK | HIF1A 2000/4885EPAS1 870/4885MEN1 4341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.