Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | FABP7 | O15540 | 1/20 | 0.47 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664146 | 0.87 | TSHR (0.58) | TSHRL3MBTL1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL6666657 | 0.86 | FABP7 (0.58) | TSHRL3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL280126 | 0.86 | FABP7 (0.58) | TSHRL3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL10917021 | 0.86 | FABP7 (0.58) | TSHRL3MBTL1ALDH1A1TDP1MAPK1 | |
| SCHEMBL17780228 | 0.86 | TSHR (0.57) | TSHRL3MBTL1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL1664712 | 0.86 | TSHR (0.57) | TSHRL3MBTL1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL6999819 | 0.86 | NPC1 (0.63) | TSHRL3MBTL1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL23655138 | 0.85 | TSHR (0.56) | TSHRL3MBTL1ALDH1A1TDP1CYP3A4 | |
| SCHEMBL1663959 | 0.85 | ALDH1A1 (0.56) | TSHRL3MBTL1ALDH1A1TDP1CYP3A4 | |
| Hydrochloric Acid SCHEMBL27765522 | 0.85 | FABP7 (0.57) | TSHRL3MBTL1ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547646-B1 | HIGH SOLVATING CYCLOHEXANE DICARBOXYLATE DIESTERS PLASTICIZERS | EASTMAN CHEM CO (US) | 2018-05-16 | — | — | EP | claimed |
| US-7973194-B1 | High solvating cyclohexane dicarboxylate diesters plasticizers | EASTMAN CHEMICAL COMPANY (US) | 2011-07-05 | — | — | US | claimed |
| US-10550242-B2 | Plasticiser composition containing aliphatic dicarboxylic acid esters and diesters selected from 1,2-cyclohexane dicarboxylic acid esters and terephthalic acid esters | BASF SE (DE) | 2020-02-04 | — | — | US | disclosed |
| US-10329402-B2 | Plasticizer composition which comprises cycloalkyl esters of saturated dicarboxylic acids and 1,2-cyclohexanedicarboxylic esters | BASF SE (DE) | 2019-06-25 | — | — | US | disclosed |
| US-10287415-B2 | Plasticizer composition which comprises cycloalkyl esters of saturated dicarboxylic acids and terephthalic esters | BASF SE (DE) | 2019-05-14 | — | — | US | disclosed |
| EP-3204448-B1 | PLASTICIZER COMPOSITION WHICH COMPRISES CYCLOALKYL ESTERS OF SATURATED DICARBOXYLIC ACIDS AND 1,2-CYCLOHEXANEDICARBOXYLIC ESTERS | BASF SE (DE) | 2018-10-03 | — | — | EP | disclosed |
| US-10072133-B2 | Plasticizer composition containing furan derivatives and 1,2-cyclohexanedicarboxylic ester | BASF SE (DE) | 2018-09-11 | — | — | US | disclosed |
| US-10030120-B2 | Softener composition which contains tetrahydrofuran derivatives and 1,2-cyclohexane dicarboxylic acid esters | BASF SE (DE) | 2018-07-24 | — | — | US | disclosed |
| EP-3204447-B1 | PLASTICIZER COMPOSITION WHICH COMPRISES CYCLOALKYL ESTERS OF SATURATED DICARBOXYLIC ACIDS AND TEREPHTHALIC ESTERS | BASF SE (DE) | 2018-07-18 | — | — | EP | disclosed |
| EP-2547646-B1 | HIGH SOLVATING CYCLOHEXANE DICARBOXYLATE DIESTERS PLASTICIZERS | EASTMAN CHEM CO (US) | 2018-05-16 | — | — | EP | disclosed |
| US-20170313848-A1 | PLASTICIZER COMPOSITION WHICH COMPRISES CYCLOALKYL ESTERS OF SATURATED DICARBOXYLIC ACIDS AND TEREPHTHALIC ESTERS | BASF SE (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170145187-A1 | PLASTICIZER COMPOSITION WHICH CONTAINS ALIPHATIC DICARBOXYLIC ACID ESTERS UND TEREPHTHALIC ACID DIALKYL ESTERS | BASF SE (DE) | 2017-05-25 | — | — | US | disclosed |
| US-20170044352-A1 | PLASTICIZER COMPOSITION WHICH CONTAINS FURAN DERIVATIVES AND TEREPHTHALIC ACID DIALKYL ESTERS | BASF SE (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20160326347-A1 | PLASTICIZER COMPOSITION CONTAINING FURAN DERIVATIVES AND 1,2-CYCLOHEXANEDICARBOXYLIC ESTER | BASF SE (DE) | 2016-11-10 | — | — | US | disclosed |
| US-20160312004-A1 | SOFTENER COMPOSITION WHICH CONTAINS TETRAHYDROFURAN DERIVATIVES AND 1,2-CYCLOHEXANE DICARBOXYLIC ACID ESTERS | BASF SE (DE) | 2016-10-27 | — | — | US | disclosed |
| US-20160215119-A1 | TETRAHYDROFURAN DERIVATIVES AND THEIR USE AS PLASTICIZERS | BASF SE (DE) | 2016-07-28 | — | — | US | disclosed |
| WO-2016055573-A1 | PLASTICIZER COMPOSITION WHICH COMPRISES CYCLOALKYL ESTERS OF SATURATED DICARBOXYLIC ACIDS AND 1,2-CYCLOHEXANEDICARBOXYLIC ESTERS | BASF SE (DE) | 2016-04-14 | — | — | WO | disclosed |
| WO-2016055572-A1 | PLASTICIZER COMPOSITION WHICH COMPRISES CYCLOALKYL ESTERS OF SATURATED DICARBOXYLIC ACIDS AND TEREPHTHALIC ESTERS | BASF SE (DE) | 2016-04-14 | — | — | WO | disclosed |
| US-20160075671-A1 | TETRAHYDROFURAN DERIVATIVES AND USE THEREOF AS PLASTICIZERS | BASF SE (DE) | 2016-03-17 | — | — | US | disclosed |
| US-7973194-B1 | High solvating cyclohexane dicarboxylate diesters plasticizers | EASTMAN CHEMICAL COMPANY (US) | 2011-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160215119-A1 | TETRAHYDROFURAN DERIVATIVES AND THEIR USE AS PLASTICIZERS | DHPS, MTHFD2, TERT | TSHR 4799/4885L3MBTL1 3729/4885ALDH1A1 278/4885 |
| US-20160075671-A1 | TETRAHYDROFURAN DERIVATIVES AND USE THEREOF AS PLASTICIZERS | CBR3, CBR1, TERT | TSHR 4601/4885L3MBTL1 3061/4885ALDH1A1 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.