SCHEMBL217540

SCHEMBL217540

CN(C)c1ccc2c(c1N(C)C)[CH]c1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.36
NEK2 P51955 1/20 0.36
LIMK1 P53667 1/20 0.36
DYRK1A Q13627 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
ALDH1A1 P00352 2/20 0.33
LMNA P02545 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
NSD2 O96028 1/20 0.33
EGFR P00533 1/20 0.33
MAPT P10636 1/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
USP2 O75604 1/20 0.33
POLB P06746 1/20 0.33
EP300 Q09472 1/20 0.32
KAT2B Q92831 1/20 0.32
KAT8 Q9H7Z6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215956 0.81 MAPT (0.43) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL9412835 0.80 ALDH1A1 (0.33) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL4719924 0.68 TP53 (0.33) ALDH1A1LMNAL3MBTL1TDP1NSD2
SCHEMBL9757011 0.67 GAA (0.39) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL218438 0.67 TSHR (0.34) ALDH1A1L3MBTL1TDP1NSD2MAPT
SCHEMBL4721790 0.66 DRD3 (0.35) ALDH1A1LMNAL3MBTL1TDP1NSD2
SCHEMBL216981 0.66 ACHE (0.39) ALDH1A1LMNATDP1CYP1A2TSHR
SCHEMBL6676649 0.66 PGR (0.42) ALDH1A1LMNAMAPTMEN1KMT2A
SCHEMBL18984780 0.66 ALDH1A1 (0.66) ALDH1A1LMNAL3MBTL1TDP1NSD2
SCHEMBL4722979 0.66 MEN1 (0.36) ALDH1A1L3MBTL1MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-20140066567-A1 Multiple Catalyst System for Olefin Polymerization and Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2014-03-06 US disclosed
US-8563647-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2013-10-22 US disclosed
EP-1620479-B1 POLYOLEFIN ADHESIVE COMPOSITIONS AND ARTICLES MADE THEREFROM EXXONMOBIL CHEM PATENTS INC (US) 2013-07-24 EP disclosed
EP-1558655-B1 MULTIPLE CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEM PATENTS INC (US) 2012-08-29 EP disclosed
US-20120095157-A1 Multiple Catalyst System For Olefin Polymerization And Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2012-04-19 US disclosed
US-8088867-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-01-03 US disclosed
US-8071687-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-12-06 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
US-7524910-B2 Polyolefin adhesive compositions and articles made therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-04-28 US disclosed
US-20090069475-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2009-03-12 US disclosed
EP-1964860-A1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER Tosoh Corporation (JP) 2008-09-03 EP disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed