Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418597 | 0.85 | POLB (0.55) | POLBMMEALDH1A1GAAHTT | |
| SCHEMBL8644189 | 0.83 | TSHR (0.58) | POLBMMEALDH1A1GAAHTT | |
| SCHEMBL6462222 | 0.80 | HTT (0.57) | POLBALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL21210729 | 0.79 | POLB (0.63) | POLBALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL2666190 | 0.78 | ALDH1A1 (0.71) | POLBALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL26741187 | 0.78 | ALDH1A1 (0.60) | POLBALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL26741146 | 0.78 | ALDH1A1 (0.60) | POLBALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL15607632 | 0.78 | SMN1; SMN2 (0.62) | POLBMMEALDH1A1GAAHTT | |
| SCHEMBL6795826 | 0.77 | POLB (0.69) | POLBALDH1A1GAASMN1; SMN2NPC1 | |
| SCHEMBL6799235 | 0.77 | POLB (0.69) | POLBALDH1A1GAASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10570153-B2 | Benzodiazepine derivatives as RSV inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2020-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10570153-B2 | Benzodiazepine derivatives as RSV inhibitors | GABRA5, GABRA1, GABBR2 | POLB 4513/4885MME 1185/4885ALDH1A1 621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.