Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26025734 | 0.82 | RIPK1 (0.31) | — | |
| SCHEMBL21756951 | 0.75 | GABRA1 (0.31) | — | |
| SCHEMBL8371348 | 0.71 | DHODH (0.39) | SLC6A4 | |
| SCHEMBL24460269 | 0.71 | SLC6A4 (0.49) | SLC6A4 | |
| SCHEMBL8180613 | 0.68 | CSNK2A1 (0.41) | — | |
| SCHEMBL30079214 | 0.67 | GCGR (0.34) | — | |
| SCHEMBL11916150 | 0.66 | KCNQ3 (0.34) | — | |
| SCHEMBL20625297 | 0.66 | KCNQ3 (0.32) | — | |
| SCHEMBL5240307 | 0.66 | ACHE (0.38) | — | |
| SCHEMBL15576311 | 0.66 | RXRA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020039092-A2 | NOVEL AROMATIC MOLECULES | Xeniopro GmbH (DE) | 2020-02-27 | — | — | WO | disclosed |
| US-9403829-B2 | Pharmaceutical compositions of 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino [2,3-b]pyrazin-2(1H)-one, a solid form thereof and methods of their use | SIGNAL PHARMACEUTICALS, LLC (US) | 2016-08-02 | — | — | US | disclosed |