Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.34 |
| ▸ | ADH1A | P07327 | 4/20 | 0.34 |
| ▸ | ADH1C | P00326 | 3/20 | 0.32 |
| ▸ | ADH7 | P40394 | 2/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | UBE2M | P61081 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928027 | 0.79 | ADH1B (0.43) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL172647 | 0.76 | ADH1B (0.40) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL18535053 | 0.75 | ADH1B (0.42) | ADH1BADH1AADH1CADH7ADH4 | |
| Hydrochloric Acid SCHEMBL28446459 | 0.74 | ADH1B (0.41) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL25043754 | 0.74 | ADH1B (0.46) | ADH1BADH1AADH1CADH7ADH4 | |
| Hydrochloric Acid SCHEMBL28439550 | 0.72 | ADH1B (0.45) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL1781920 | 0.71 | ADH1B (0.52) | ADH1BADH1AADH1CADH7ADH4 | |
| SCHEMBL17729334 | 0.70 | GNAI3 (0.37) | — | |
| SCHEMBL14504027 | 0.70 | ADH1B (0.46) | ADH1BADH1AADH1CADH7ADH4 | |
| Hydrochloric Acid SCHEMBL28635747 | 0.70 | GNAO1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215509-B1 | SUBSTITUTED PYRROLO[1,2-A]PYRIMIDINES AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | LYSOSOMAL THERAPEUTICS INC (US) | 2020-02-26 | — | — | EP | disclosed |