Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 4/20 | 0.40 |
| ▸ | ADH1A | P07327 | 4/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 3/20 | 0.38 |
| ▸ | ADH7 | P40394 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | DRD3 | P35462 | 3/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 2/20 | 0.37 |
| ▸ | DRD5 | P21918 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28625285 | 0.85 | GNAO1 (0.55) | GNAI3GNAO1GNAI1 | |
| Hydrochloric Acid SCHEMBL28635747 | 0.85 | GNAO1 (0.55) | GNAI3GNAO1GNAI1 | |
| SCHEMBL3928027 | 0.85 | ADH1B (0.43) | ADH1BADH1AEPHX1EPHX2L3MBTL1 | |
| SCHEMBL28313628 | 0.79 | GNAI3 (0.50) | ADH1BADH1AEPHX1EPHX2ADH1C | |
| SCHEMBL28267489 | 0.77 | GNAO1 (0.56) | ADH1BADH1AEPHX1EPHX2ADH1C | |
| SCHEMBL12995614 | 0.77 | HRH2 (0.43) | EPHX1EPHX2L3MBTL1PABPC1DRD2 | |
| SCHEMBL16380998 | 0.77 | HRH2 (0.43) | EPHX1EPHX2L3MBTL1PABPC1DRD2 | |
| SCHEMBL13874921 | 0.77 | HRH2 (0.43) | EPHX1EPHX2L3MBTL1PABPC1DRD2 | |
| SCHEMBL1781920 | 0.77 | ADH1B (0.52) | ADH1BADH1AEPHX1EPHX2L3MBTL1 | |
| SCHEMBL22702138 | 0.77 | EPHX1 (0.35) | EPHX1EPHX2L3MBTL1PABPC1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |