SCHEMBL21758022

SCHEMBL21758022

Cc1cc2c3c(c1)Oc1cc4c(cc1B3c1ccccc1O2)B1c2ccccc2Oc2cc(C)cc(c21)O4

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24237989 1.00 LMNA (0.30) LMNATP53
SCHEMBL20409587 0.93 LMNA (0.33) LMNATP53
SCHEMBL26997835 0.90
SCHEMBL25635411 0.90 LMNA (0.35) LMNATP53
SCHEMBL21666861 0.89 TP53 (0.35) TP53
SCHEMBL21758020 0.87
SCHEMBL26997806 0.87 TP53 (0.31) TP53
SCHEMBL24237300 0.87 ALOX5 (0.33)
SCHEMBL22599924 0.86 MAOA (0.30)
SCHEMBL24238109 0.86 AHR (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200190115-A1 POLYCYCLIC AROMATIC COMPOUND KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-06-18 US disclosed
WO-2020045681-A1 ORGANIC ELECTROLUMINESCENT ELEMENT USING LIGHT EMITTING MATERIAL COMPOSED OF POLYCYCLIC AROMATIC COMPOUND 学校法人関西学院 2020-03-05 WO disclosed
WO-2020040298-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, ILLUMINATION DEVICE, LUMINESCENT LAYER FORMING COMPOSITION, AND COMPOUND 学校法人関西学院 2020-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190115-A1 POLYCYCLIC AROMATIC COMPOUND ETV6, EML4, ELOC LMNA 3046/4885TP53 1658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.