Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831805 | 0.90 | L3MBTL1 (0.64) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL5684329 | 0.85 | SRD5A1 (0.45) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5357579 | 0.85 | ALDH1A1 (0.59) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL16064651 | 0.81 | SRD5A1 (0.51) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL29809412 | 0.81 | SRD5A1 (0.47) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL16044075 | 0.81 | SRD5A1 (0.47) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL7662248 | 0.79 | SRD5A1 (0.42) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL12514886 | 0.79 | ALDH1A1 (0.38) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL8458964 | 0.78 | SRD5A1 (0.49) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL14711693 | 0.78 | SRD5A1 (0.45) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200061039-A1 | PYRIDINONE COMPOUND AND USE THEREOF | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200061039-A1 | PYRIDINONE COMPOUND AND USE THEREOF | DOCK5, DOCK2, CIB1 | RAB9A 533/4885NPC1 3370/4885ALDH1A1 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.