Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9413909 | 0.81 | LMNA (0.61) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL9413911 | 0.81 | LMNA (0.61) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL3437188 | 0.76 | MAPT (0.48) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL3951014 | 0.76 | MAPT (0.48) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL21758832 | 0.72 | ALDH1A1 (0.46) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL13177035 | 0.72 | ALDH1A1 (0.51) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL14027510 | 0.72 | MAPT (0.48) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| Acrylonitrile SCHEMBL29191949 | 0.70 | KDM4E (0.44) | LMNAALDH1A1MAPTHDAC3HDAC4 | |
| SCHEMBL15722626 | 0.69 | AKR1B10 (0.63) | LMNAALDH1A1AKR1B10AKR1B1MAOB | |
| SCHEMBL5007755 | 0.69 | AKR1B10 (0.63) | LMNAALDH1A1MAPTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |