Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.41 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17615394 | 0.78 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL23981734 | 0.74 | RAB9A (0.42) | ALDH1A1MAPTSMN1; SMN2CYP1B1NPC1 | |
| SCHEMBL9043653 | 0.74 | HDAC3 (0.49) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL21758829 | 0.72 | LMNA (0.42) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL9715784 | 0.72 | EGFR (0.51) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL31678901 | 0.72 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL3437188 | 0.72 | MAPT (0.48) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL3951014 | 0.72 | MAPT (0.48) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL1232441 | 0.72 | MAPT (0.48) | ALDH1A1LMNAMAPTHDAC3HDAC4 | |
| SCHEMBL20192382 | 0.72 | MAPT (0.48) | ALDH1A1LMNAMAPTHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021221760-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING TO INCLUDE LONG CHAIN CARBON AND CYCLIC AMINO ACIDS | NORTHWESTERN UNIVERSITY (US) | 2021-11-04 | — | — | WO | disclosed |
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |