Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 5/20 | 0.31 |
| ▸ | MAOB | P27338 | 5/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21758757 | 0.85 | GSK3B (0.43) | GSK3B | |
| SCHEMBL21758846 | 0.78 | CYP19A1 (0.41) | MAOAMAOB | |
| SCHEMBL21758849 | 0.78 | ALDH1A1 (0.37) | GSK3B | |
| SCHEMBL21758828 | 0.77 | MAOA (0.44) | MAOAMAOB | |
| SCHEMBL21758833 | 0.74 | ALDH1A1 (0.38) | — | |
| SCHEMBL21758759 | 0.74 | ALDH1A1 (0.37) | MAOAMAOB | |
| SCHEMBL21758843 | 0.70 | MEN1 (0.30) | — | |
| SCHEMBL8585794 | 0.68 | ALDH1A1 (0.46) | MAOAMAOBGSK3B | |
| SCHEMBL23950227 | 0.66 | HDAC8 (0.39) | CTSLCTSBCTSSMAOAMAOB | |
| SCHEMBL13784878 | 0.66 | CA12 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021221760-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING TO INCLUDE LONG CHAIN CARBON AND CYCLIC AMINO ACIDS | NORTHWESTERN UNIVERSITY (US) | 2021-11-04 | — | — | WO | disclosed |
| WO-2020040840-A2 | EXPANDING THE CHEMICAL SUBSTRATES FOR GENETIC CODE REPROGRAMMING | NORTHWESTERN UNIVERSITY (US) | 2020-02-27 | — | — | WO | disclosed |