Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23585476 | 0.89 | OPRM1 (0.36) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL21760842 | 0.81 | LMNA (0.33) | MEN1KMT2AMAPT | |
| SCHEMBL696381 | 0.73 | MEN1 (0.43) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL21760985 | 0.72 | MAPT (0.64) | MEN1KMT2AMAPTPKMHTT | |
| SCHEMBL21760987 | 0.72 | ALDH1A1 (0.41) | MEN1KMT2AMAPTPKMHTT | |
| SCHEMBL14709959 | 0.70 | OPRM1 (0.39) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 | |
| SCHEMBL23585562 | 0.68 | PIK3CA (0.32) | — | |
| SCHEMBL21761019 | 0.68 | F2RL3 (0.32) | MEN1KMT2AMAPT | |
| SCHEMBL21761014 | 0.68 | MEN1 (0.37) | MEN1KMT2AMAPTPKMHTT | |
| SCHEMBL22397059 | 0.65 | POLB (0.51) | OPRM1OPRD1OPRK1SLC22A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842439-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |