Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | PKM | P14618 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21760987 | 0.76 | ALDH1A1 (0.41) | MAPTMEN1KMT2APKMHTT | |
| SCHEMBL2431619 | 0.75 | MEN1 (0.45) | MAPTMEN1KMT2APKMHTT | |
| SCHEMBL21138063 | 0.73 | TP53 (0.65) | MAPTPKMSMN1; SMN2TP53NPC1 | |
| SCHEMBL15349939 | 0.72 | TP53 (0.50) | MAPTKMT2APKMF2RL3SMN1; SMN2 | |
| SCHEMBL21761027 | 0.72 | OPRM1 (0.39) | MAPTMEN1KMT2APKMHTT | |
| SCHEMBL21761014 | 0.71 | MEN1 (0.37) | MAPTMEN1KMT2APKMHTT | |
| SCHEMBL12210699 | 0.71 | MEN1 (0.48) | MAPTMEN1KMT2APKMHTT | |
| SCHEMBL16742697 | 0.70 | MEN1 (0.40) | MAPTMEN1KMT2APKMHTT | |
| SCHEMBL696137 | 0.70 | MEN1 (0.51) | MAPTMEN1KMT2APKMHTT | |
| SCHEMBL2658210 | 0.68 | PKM (0.51) | MAPTMEN1KMT2APKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842439-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-06-30 | — | — | EP | disclosed |
| WO-2020040104-A1 | BICYCLIC HETEROAROMATIC RING DERIVATIVE | 杏林製薬株式会社 | 2020-02-27 | — | — | WO | disclosed |