Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | LTK | P29376 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.33 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21787759 | 0.82 | HPGD (0.44) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL21787761 | 0.82 | GPR3 (0.39) | ALDH1A1F9HPGDKDM4EMAPT | |
| SCHEMBL15306211 | 0.81 | TACR1 (0.34) | ALDH1A1HSD17B10TACR1HPRT1MAP4K4 | |
| SCHEMBL21787996 | 0.80 | ALDH1A1 (0.40) | ALDH1A1HSD17B10HPGDKDM4EMEN1 | |
| SCHEMBL18960517 | 0.79 | MAOA (0.39) | ALDH1A1HSD17B10TACR1LIMK1CLK4 | |
| SCHEMBL24029649 | 0.79 | CRHR1 (0.33) | ALDH1A1TACR1HPGDKDM4EMEN1 | |
| SCHEMBL24029642 | 0.79 | CRHR1 (0.33) | ALDH1A1TACR1HPGDKDM4EMEN1 | |
| SCHEMBL24029644 | 0.79 | CRHR1 (0.33) | ALDH1A1TACR1HPGDKDM4EMEN1 | |
| SCHEMBL21764381 | 0.79 | CRHR1 (0.33) | ALDH1A1TACR1HPGDKDM4EMEN1 | |
| SCHEMBL15306208 | 0.79 | CRHR1 (0.33) | ALDH1A1TACR1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3369719-B1 | SPIRO-TYPE COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2020-02-26 | — | — | EP | disclosed |