Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21992412 | 0.87 | CYP2C19 (0.38) | ALDH1A1HSD17B10TDP1MAPK1HPGD | |
| SCHEMBL15866441 | 0.85 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TAAR1CYP3A4TDP1 | |
| SCHEMBL18960517 | 0.83 | MAOA (0.39) | ALDH1A1HSD17B10DPP4BCL2L1MAPK1 | |
| SCHEMBL21992411 | 0.83 | ABL1 (0.45) | ALDH1A1TDP1HPGDNPC1RAB9A | |
| SCHEMBL21763288 | 0.80 | ALDH1A1 (0.34) | ALDH1A1HSD17B10DPP4BCL2L1MAPK1 | |
| SCHEMBL15372074 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TAAR1CYP3A4TDP1 | |
| SCHEMBL16385447 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TAAR1CYP3A4TDP1 | |
| SCHEMBL15038395 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TAAR1CYP3A4TDP1 | |
| SCHEMBL15038424 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TAAR1CYP3A4TDP1 | |
| SCHEMBL6212117 | 0.79 | ALDH1A1 (0.39) | ALDH1A1HSD17B10TAAR1CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220006020-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2022-01-06 | — | — | US | disclosed |
| US-20200075862-A1 | INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | DOTTIKON ES HOLDING AG (CH) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220006020-A1 | DI-, TRI- AND TETRAPHENYLINDANE DERIVATES AND THEIR USE IN ORGANIC ELECTRONICS | NR0B2, KCNJ2, TRRAP | ALDH1A1 2569/4885HSD17B10 4262/4885TAAR1 111/4885 |
| US-20200075862-A1 | INDANE DERIVATIVES AND THEIR USE IN ORGANIC ELECTRONICS | KCNJ2, KCNA2, CYP2J2 | ALDH1A1 1964/4885HSD17B10 3054/4885TAAR1 521/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.