SCHEMBL2176453

SCHEMBL2176453

CC(SSc1ccccn1)c1ccccc1C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 2/20 0.34
LMNA P02545 3/20 0.34
MAPK10 P53779 1/20 0.34
MEN1 O00255 4/20 0.33
KMT2A Q03164 4/20 0.33
EHMT2 Q96KQ7 1/20 0.33
EHMT1 Q9H9B1 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
HPGD P15428 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.32
HCRTR2 O43614 1/20 0.32
TSHR P16473 2/20 0.31
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29389017 1.00 RAB9A (0.34) RAB9ALMNAMAPK10MEN1KMT2A
SCHEMBL29386113 0.83 MAPT (0.36) RAB9ALMNAMEN1KMT2AEHMT2
SCHEMBL42875 0.83 MAPT (0.36) RAB9ALMNAMEN1KMT2AEHMT2
SCHEMBL5153054 0.80 SMN1; SMN2 (0.39) RAB9ALMNAMEN1KMT2AEHMT2
SCHEMBL8341133 0.77 KDM4E (0.39) MEN1KMT2ASMN1; SMN2KDM4ETSHR
SCHEMBL29351145 0.77 LMNA (0.38) RAB9ALMNAMEN1KMT2AEHMT2
SCHEMBL321113 0.77 LMNA (0.38) RAB9ALMNAMEN1KMT2AEHMT2
SCHEMBL8610607 0.77 LMNA (0.38) RAB9ALMNAMEN1KMT2AEHMT2
SCHEMBL1746858 0.76 ALDH1A1 (0.35) RAB9ALMNAMAPK10MEN1KMT2A
SCHEMBL5502675 0.76 LMNA (0.36) RAB9ALMNAMAPK10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111902148-B Compositions and methods for treating muscular atrophy and tonic muscular dystrophy 艾维迪提生物科学公司 2024-07-05 CN disclosed
CN-118267396-A Nucleic acid-polypeptide compositions and uses thereof 艾维迪提生物科学公司 2024-07-02 CN disclosed
CN-118265544-A Compositions and methods for treating facial shoulder brachial muscular dystrophy 艾维迪提生物科学公司 2024-06-28 CN disclosed
CN-113929738-B Antibody-drug conjugates 第一三共株式会社 2024-05-17 CN disclosed
CN-116063505-B Anti-GAL 3 antibodies and uses thereof 真和制药有限公司 2024-05-03 CN disclosed
CN-117916269-A Method for preventing aggregation of proteins 真和制药有限公司 2024-04-19 CN disclosed
CN-117897406-A anti-GAL 3 antibodies and methods for their use in insulin resistance 真和制药有限公司 2024-04-16 CN disclosed
CN-111655268-B Nucleic acid-polypeptide compositions and uses thereof 艾维迪提生物科学公司 2024-03-26 CN disclosed
CN-113423735-B Anti-claudin antibodies and uses thereof 再鼎医药(上海)有限公司 2024-02-13 CN disclosed
CN-117561080-A anti-GAL 3 antibody formulations and methods of use thereof 真和制药有限公司 2024-02-13 CN disclosed
EP-1781685-A1 THERAPEUTIC AND DIAGNOSTIC AGENTS The Walter and Eliza Hall Institute of Medical Research (AU) 2007-05-09 EP disclosed
US-7048929-B1 approximates conformational discontinuous epitopes of a primate lentivirus envelope protein, modifications of the structure has enhanced stability, raises a greater range of antibodies to conserved epitopes, and/or has enhanced immunogenicity for broadly neutralizing epitopes. DANA-FARBER CANCER INSTITUTE, INC. (US) 2006-05-23 US disclosed
US-20060067944-A1 Stable immunogenic product comprising antigenic heterocomplexes NEOVACS (FR) 2006-03-30 US disclosed
WO-2006007667-A1 THERAPEUTIC AND DIAGNOSTIC AGENTS THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) 2006-01-26 WO disclosed
US-20060013800-A1 Stable immunogenic product comprising antigenic heterocomplexes NEOVACS (FR) 2006-01-19 US disclosed
US-20050170439-A1 Methods for Detecting Receptor Complexes Comprising PI3K ACLARA BIOSCIENCES, INC. 2005-08-04 US disclosed
US-20050170438-A1 Methods for Detecting Receptor Complexes Comprising PDGFR MONOGRAM BIOSCIENCES, INC. 2005-08-04 US disclosed
US-20040253636-A1 Method of protein analysis OXFORD GLYCOSCIENCES (UK) LTD. (GB) 2004-12-16 US disclosed
EP-1430307-A2 A METHOD OF PROTEIN ANALYSIS Oxford GlycoSciences (UK) Ltd, Attn: Mary Gadsden (GB) 2004-06-23 EP disclosed
WO-2003027681-A2 A METHOD OF PROTEIN ANALYSIS OXFORD GLYCOSCIENCES (UK) LTD (GB) 2003-04-03 WO disclosed