SCHEMBL5502675

SCHEMBL5502675

CCc1cccc(C(=O)ON2C(=O)CCC2=O)c1SSc1ccccn1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
RAB9A P51151 4/20 0.35
EHMT2 Q96KQ7 1/20 0.35
EHMT1 Q9H9B1 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
MAPK10 P53779 1/20 0.35
ALDH1A1 P00352 4/20 0.34
POLB P06746 2/20 0.34
KDM4E B2RXH2 1/20 0.33
HCRTR2 O43614 2/20 0.33
SMN1; SMN2 Q16637 4/20 0.33
TDP1 Q9NUW8 1/20 0.32
NPC1 O15118 3/20 0.32
MAPT P10636 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HCRTR1 O43613 1/20 0.32
CASP3 P42574 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4070360 0.82 LMNA (0.35) LMNARAB9AEHMT2EHMT1APOBEC3G
SCHEMBL1746858 0.82 ALDH1A1 (0.35) LMNARAB9AEHMT2EHMT1APOBEC3G
SCHEMBL73690 0.81 EHMT2 (0.37) LMNARAB9AEHMT2EHMT1APOBEC3G
SCHEMBL28514925 0.79 LMNA (0.45) LMNARAB9AEHMT2EHMT1APOBEC3G
SCHEMBL561821 0.78 RAB9A (0.37) LMNARAB9AEHMT2EHMT1APOBEC3G
SCHEMBL1374041 0.77 GCK (0.39) LMNARAB9AALDH1A1POLBL3MBTL1
SCHEMBL19209537 0.77 APOBEC3G (0.40) LMNARAB9AEHMT2EHMT1APOBEC3G
SCHEMBL13700039 0.77 KDM4E (0.42) LMNAALDH1A1POLBKDM4ESMN1; SMN2
SCHEMBL30392206 0.76 MEN1 (0.41) LMNARAB9AMAPK10ALDH1A1POLB
SCHEMBL28384909 0.76 MEN1 (0.41) LMNARAB9AMAPK10ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149534-A1 HAPTENIZED CORONAVIRUS SPIKE PROTEINS BIOVAXYS LLC 2023-05-18 US disclosed
WO-2023060220-A1 METHODS OF IMMUNIZATION AGAINST CORONAVIRUS BioVaxys Inc. (US) 2023-04-13 WO disclosed
EP-4121103-A1 HAPTENIZED CORONAVIRUS SPIKE PROTEINS BioVaxys Inc. (US) 2023-01-25 EP disclosed
WO-2021188991-A1 HAPTENIZED CORONAVIRUS SPIKE PROTEINS BioVaxys Inc. (US) 2021-09-23 WO disclosed
CN-112165952-A SAP and peptidomimetic compositions for reducing inflammatory symptoms 阿奇生物外科有限公司 2021-01-01 CN disclosed
CN-112165954-A SAP and peptidomimetics for treating ocular diseases 阿奇生物外科有限公司 2021-01-01 CN disclosed
US-20140113371-A1 Cryopreservation of Haptenized Tumor Cells BERD DAVID (US) 2014-04-24 US disclosed
US-8435784-B2 Cryopreservation of haptenized tumor cells THOMAS JEFFERSON UNIVERSITY 2013-05-07 US disclosed
US-20070237795-A1 Cryopreservation of Haptenized Tumor Cells AVAX TECHNOLOGIES, INC. 2007-10-11 US disclosed
US-20050233301-A1 Cryopreservation of haptenized tumor cells BERD DAVID 2005-10-20 US disclosed
EP-1551225-A2 CRYOPRESERVATION OF HAPTENIZED TUMOR CELLS Avax Technologies Inc. (US) 2005-07-13 EP disclosed
WO-2003103389-A2 CRYOPRESERVATION OF HAPTENIZED TUMOR CELLS AVAX TECHNOLOGIES INC. (US) 2003-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149534-A1 HAPTENIZED CORONAVIRUS SPIKE PROTEINS ACE2, CD14, TMPRSS2 LMNA 4605/4885RAB9A 2623/4885EHMT2 2542/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.