Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19464682 | 0.88 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13018932 | 0.84 | SMN1; SMN2 (0.59) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL17680989 | 0.84 | KMT2A (0.77) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL23417746 | 0.83 | TSHR (0.51) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9620133 | 0.83 | GAA (0.77) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL5186769 | 0.83 | RAB9A (0.62) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL21765907 | 0.81 | TSHR (0.51) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11578349 | 0.81 | HPGD (0.65) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL9403860 | 0.80 | KDM4E (0.59) | MEN1KMT2AALDH1A1KDM4EPOLB | |
| SCHEMBL30296233 | 0.80 | KDM4E (0.59) | MEN1KMT2AALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470669-B1 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1997-11-12 | — | — | EP | disclosed |
| US-5164502-A | Fluorinating agents | DOWELANCO (US) | 1992-11-17 | — | — | US | disclosed |
| US-5116982-A | Fluorination | DOWELANCO (US) | 1992-05-26 | — | — | US | disclosed |
| EP-0470669-A2 | Preparation of fluorophenols, fluorohalophenols, N-acylfluoroanilines, and N-acylfluorohaloanilines | DOWELANCO (US) | 1992-02-12 | — | — | EP | disclosed |