Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30514739 | 0.93 | MAOA (0.38) | MAOAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL21751381 | 0.93 | MAOA (0.38) | MAOAALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL21751456 | 0.93 | ADORA2A (0.31) | MAOAADORA2BADORA2ATSHRHSD17B10 | |
| SCHEMBL21751374 | 0.93 | NPSR1 (0.33) | MAOATSHRHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL30800177 | 0.90 | ADORA2A (0.32) | MAOAADORA2BADORA2ATSHRHSD17B10 | |
| SCHEMBL21751428 | 0.90 | ADORA2A (0.32) | MAOAADORA2BADORA2ATSHRHSD17B10 | |
| SCHEMBL19810295 | 0.89 | CYP1A2 (0.43) | TSHRHSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30800221 | 0.89 | CYP1A2 (0.43) | TSHRHSD17B10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL21751395 | 0.89 | LTB4R (0.40) | MAOAADORA2AHSD17B10CYP1A2CYP3A4 | |
| SCHEMBL21751418 | 0.89 | SMN1; SMN2 (0.39) | MAOAHSD17B10ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119060054-A | Nitroaromatic ring substituted imidazopyrazine compound and preparation method and application thereof | 南京中医药大学 | 2024-12-03 | — | — | CN | disclosed |
| US-11691976-B2 | Coelenterazine analogues | PROMEGA CORPORATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-20200062766-A1 | COELENTERAZINE ANALOGUES | PROMEGA CORPORATION | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062766-A1 | COELENTERAZINE ANALOGUES | GLB1, SI, TCF7L2 | MAOA 3004/4885ADORA2B 3105/4885ADORA2A 1970/4885 |
| US-11691976-B2 | Coelenterazine analogues | GLB1, SI, TCF7L2 | MAOA 3004/4885ADORA2B 3105/4885ADORA2A 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.