Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19810295 | 1.00 | CYP1A2 (0.43) | CYP1A2CYP2C19HSD17B10CYP3A4CYP2D6 | |
| SCHEMBL19810194 | 0.91 | ALDH1A1 (0.39) | CYP1A2CYP2C19HSD17B10CYP3A4ALOX15 | |
| SCHEMBL25760270 | 0.90 | ADORA2B (0.38) | HSD17B10ALOX15TSHRLMNASMN1; SMN2 | |
| SCHEMBL21767317 | 0.89 | MAOA (0.36) | CYP1A2CYP2C19HSD17B10CYP3A4CYP2D6 | |
| SCHEMBL2670126 | 0.89 | ALDH1A1 (0.39) | HSD17B10ALOX15TSHRLMNAHTT | |
| SCHEMBL19206678 | 0.88 | LTB4R (0.47) | CYP1A2CYP2C19HSD17B10CYP3A4CYP2D6 | |
| SCHEMBL19810311 | 0.88 | ADORA2A (0.35) | HSD17B10ALOX15TSHRLMNASMN1; SMN2 | |
| SCHEMBL30110483 | 0.88 | ALDH1A1 (0.38) | HSD17B10TSHRLMNASMN1; SMN2HTT | |
| SCHEMBL19810232 | 0.88 | ALDH1A1 (0.38) | HSD17B10TSHRLMNASMN1; SMN2HTT | |
| SCHEMBL27213496 | 0.88 | ALDH1A1 (0.41) | CYP1A2CYP2C19HSD17B10CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513188-B | Coelenterazine analogs | 普洛麦格公司 | 2024-01-26 | — | — | CN | disclosed |