SCHEMBL21767973

SCHEMBL21767973

NNc1cc(C(F)(F)C(F)(F)F)ncn1

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.38
CHKA P35790 1/20 0.38
GAA P10253 2/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21767967 0.84 CA2 (0.55) CA2CHKAGAAALDH1A1MAPT
SCHEMBL17740837 0.74 CA2 (0.69) CA2CHKA
SCHEMBL4076540 0.73 L3MBTL1 (0.42) GAAALDH1A1MAPTRAB9A
SCHEMBL602858 0.69 CA2 (0.38) CA2CHKA
SCHEMBL601122 0.65 KMO (0.37) CA2CHKA
SCHEMBL600884 0.65 CA2 (0.34) CA2CHKA
SCHEMBL10223568 0.65 CA2 (0.34) CA2CHKA
SCHEMBL2491280 0.64
SCHEMBL30044827 0.64
SCHEMBL564890 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3617207-B1 CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND OR THE SALT, AND METHOD FOR USING THE INSECTICIDE NIHON NOHYAKU CO LTD (JP) 2023-06-28 EP disclosed
EP-3617207-B1 CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND OR THE SALT, AND METHOD FOR USING THE INSECTICIDE NIHON NOHYAKU CO LTD (JP) 2023-06-28 EP disclosed
CN-110582498-B Condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide containing the same, and method of using the same 日本农药株式会社 2022-06-24 CN disclosed
US-11064699-B2 Condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound or the salt, and method for using the insecticide NIHON NOHYAKU CO., LTD. (JP) 2021-07-20 US disclosed
US-11064699-B2 Condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound or the salt, and method for using the insecticide NIHON NOHYAKU CO., LTD. (JP) 2021-07-20 US disclosed
US-20200068893-A1 CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND OR THE SALT, AND METHOD FOR USING THE INSECTICIDE NIHON NOHYAKU CO., LTD. (JP) 2020-03-05 US disclosed
US-20200068893-A1 CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND OR THE SALT, AND METHOD FOR USING THE INSECTICIDE NIHON NOHYAKU CO., LTD. (JP) 2020-03-05 US disclosed
EP-3617207-A1 FUSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL OR HORTICULTURAL INSECTICIDE CONTAINING EITHER COMPOUND, AND METHOD FOR USING SAID INSECTICIDE Nihon Nohyaku Co., Ltd. (JP) 2020-03-04 EP disclosed
EP-3617207-A1 FUSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL OR HORTICULTURAL INSECTICIDE CONTAINING EITHER COMPOUND, AND METHOD FOR USING SAID INSECTICIDE Nihon Nohyaku Co., Ltd. (JP) 2020-03-04 EP disclosed
CN-110582498-A Condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide containing the same, and method of using the same 日本农药株式会社 2019-12-17 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200068893-A1 CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND OR THE SALT, AND METHOD FOR USING THE INSECTICIDE H1-0, H1-3, H1-2 CA2 226/4885CHKA 2665/4885GAA 4812/4885
US-11064699-B2 Condensed heterocyclic compound or salt thereof, agricultural and horticultural insecticide comprising the compound or the salt, and method for using the insecticide H1-0, H1-3, H1-2 CA2 226/4885CHKA 2665/4885GAA 4812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.