Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 4/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20332531 | 0.91 | KMT2A (0.42) | EPHX1DRD4CTDSP1TDP1PARP1 | |
| SCHEMBL21772587 | 0.89 | SIGMAR1 (0.39) | EPHX1DRD4L3MBTL1LMNA | |
| SCHEMBL7553178 | 0.88 | KDM5A (0.40) | EPHX1DRD4CTDSP1TDP1CHRM3 | |
| SCHEMBL7572847 | 0.88 | PARP1 (0.43) | PARP1L3MBTL1MEN1TSHRKMT2A | |
| SCHEMBL7572087 | 0.88 | ROCK2 (0.43) | L3MBTL1MEN1LMNATSHRMAPK1 | |
| SCHEMBL7568892 | 0.88 | KMT2A (0.48) | MEN1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7538262 | 0.87 | RAB9A (0.45) | L3MBTL1MEN1LMNATSHRMAPK1 | |
| SCHEMBL7545741 | 0.86 | PKM (0.44) | L3MBTL1MEN1LMNATSHRMAPK1 | |
| SCHEMBL7552996 | 0.85 | KMT2A (0.45) | DRD4CTDSP1TDP1L3MBTL1MEN1 | |
| SCHEMBL20304243 | 0.85 | GAA (0.43) | MEN1LMNAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200069691-A1 | HETEROCYCLIC COMPOUNDS AS HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2020-03-05 | — | — | US | claimed |
| US-20200069691-A1 | HETEROCYCLIC COMPOUNDS AS HIV PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069691-A1 | HETEROCYCLIC COMPOUNDS AS HIV PROTEASE INHIBITORS | SERPINB1, PREP, PEPD | EPHX1 848/4885DRD4 2573/4885CTDSP1 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.