Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | IKBKB | O14920 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.33 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL822716 | 0.89 | ALDH1A1 (0.43) | ALDH1A1HPGDBCL2L1HSD17B10PTPN1 | |
| SCHEMBL23280616 | 0.83 | ADORA2A (0.36) | ADORA2AALDH1A1HPGDBCL2L1HSD17B10 | |
| Allylamine SCHEMBL2187513 | 0.79 | HPGD (0.34) | ALDH1A1HPGDBCL2L1HSD17B10GABRA1 | |
| SCHEMBL20072741 | 0.79 | HPGD (0.38) | ADORA2AALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL12284074 | 0.76 | HPGD (0.41) | ALDH1A1HPGDBCL2L1HSD17B10PTPN1 | |
| SCHEMBL811780 | 0.75 | MAOA (0.39) | ALDH1A1HPGDBCL2L1HSD17B10PTPN1 | |
| SCHEMBL24925079 | 0.74 | HDAC4 (0.46) | ALDH1A1HPGDHSD17B10SMN1; SMN2MCL1 | |
| SCHEMBL20460718 | 0.73 | ALDH1A1 (0.37) | ADORA2AALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL27297316 | 0.72 | ALDH1A1 (0.45) | ALDH1A1HPGDHSD17B10SMN1; SMN2MEN1 | |
| 1-Methylimidazole SCHEMBL1082661 | 0.72 | NFKB1 (0.40) | ALDH1A1HPGDHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973191-B2 | Method for the production of dibenz[c,e] [1,2]-oxaphosphorin derivatives, amino-dibenz[c,e] [1,2]-oxaphosphorin and also use thereof | EMS-PATENT AG (CH) | 2011-07-05 | — | — | US | disclosed |
| US-20100069657-A1 | METHOD FOR THE PRODUCTION OF DIBENZ[C,E] [1,2]-OXAPHOSPHORIN DERIVATIVES, AMINO-DIBENZ[C,E] [1,2]-OXAPHOSPHORIN AND ALSO USE THEREOF | EMS-PATENT AG (CH) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069657-A1 | METHOD FOR THE PRODUCTION OF DIBENZ[C,E] [1,2]-OXAPHOSPHORIN DERIVATIVES, AMINO-DIBENZ[C,E] [1,2]-OXAPHOSPHORIN AND ALSO USE THEREOF | PFAS, PNP, PNPO | ADORA2A 443/4885ALDH1A1 1291/4885HPGD 1536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.