SCHEMBL822716

SCHEMBL822716

O=[PH](O)c1ccccc1-c1ccccc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
HPGD P15428 3/20 0.43
HSD17B10 Q99714 3/20 0.43
BCL2L1 Q07817 1/20 0.43
IDO1 P14902 2/20 0.38
MAPT P10636 3/20 0.38
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 2/20 0.38
ALOX15 P16050 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDR P35968 1/20 0.38
KDM4E B2RXH2 1/20 0.38
NPC1 O15118 1/20 0.38
CA12 O43570 1/20 0.38
GMNN O75496 1/20 0.38
EGFR P00533 1/20 0.38
CA2 P00918 1/20 0.38
FYN P06241 1/20 0.38
POLB P06746 1/20 0.38
CA3 P07451 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isopropylamine SCHEMBL2177330 0.89 ADORA2A (0.36) ALDH1A1HPGDHSD17B10BCL2L1IDO1
Allylamine SCHEMBL2187513 0.85 HPGD (0.34) ALDH1A1HPGDHSD17B10BCL2L1IDO1
SCHEMBL811780 0.84 MAOA (0.39) ALDH1A1HPGDHSD17B10BCL2L1IDO1
SCHEMBL27297316 0.81 ALDH1A1 (0.45) ALDH1A1HPGDHSD17B10MAPTSMN1; SMN2
SCHEMBL12284074 0.81 HPGD (0.41) ALDH1A1HPGDHSD17B10BCL2L1IDO1
SCHEMBL20613696 0.81 ALDH1A1 (0.41) ALDH1A1HPGDHSD17B10BCL2L1IDO1
SCHEMBL11615311 0.80 IDO1 (0.48) ALDH1A1HPGDHSD17B10IDO1MAPT
Zinc Ion SCHEMBL1083125 0.79 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10BCL2L1IDO1
SCHEMBL6013462 0.79 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10BCL2L1IDO1
SCHEMBL6013467 0.79 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10BCL2L1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118255976-A Special isosorbide-based polycarbonate and preparation method thereof 中国石油天然气股份有限公司 2024-06-28 CN disclosed
US-11760865-B2 Halogen-free sulphonic acid ester and/or sulphinic acid ester as flame retardant, flame retardant synergists and radical generators in plastics Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-09-19 US disclosed
EP-3495451-B1 FLAME RETARDANT COMPOSITION HUBER CORP J M (US) 2021-09-15 EP disclosed
US-10913743-B2 Use of organic oxyimides as flame retardant for plastic materials and also flame-retardant plastic material composition and moulded parts produced therefrom Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2021-02-09 US disclosed
US-20200231783-A1 HALOGEN-FREE SULPHONIC ACID ESTER AND/OR SULPHINIC ACID ESTER AS FLAME RETARDANT, FLAME RETARDANT SYNERGISTS AND RADICAL GENERATORS IN PLASTICS Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e. V. (DE) 2020-07-23 US disclosed
US-10544284-B2 Use of phosphorous-containing organic oxyimides as flame retardants and/or as stabilizers for plastics, flame-retardant and/or stabilized plastic compositions, method for the production thereof, moulded part, paint and coatings Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2020-01-28 US disclosed
US-20190263847-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND MARUZEN PETROCHEMICAL CO., LTD. (JP) 2019-08-29 US disclosed
US-10323136-B2 Use of hydroxybenzotriazole derivatives and/or hydroxy indazole derivatives as flame retardants for plastics and flameproof plastic moulded bodies Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2019-06-18 US disclosed
EP-3495451-A1 FLAME RETARDANT COMPOSITION J.M. Huber Corporation (US) 2019-06-12 EP disclosed
US-10221301-B2 Flame retardant composition J.M. HUBER CORPORATION (US) 2019-03-05 US disclosed
US-20100234495-A1 DOPO FLAME RETARDANT COMPOSITIONS CIBA CORPORATION (US) 2010-09-16 US disclosed
US-20100069657-A1 METHOD FOR THE PRODUCTION OF DIBENZ[C,E] [1,2]-OXAPHOSPHORIN DERIVATIVES, AMINO-DIBENZ[C,E] [1,2]-OXAPHOSPHORIN AND ALSO USE THEREOF EMS-PATENT AG (CH) 2010-03-18 US disclosed
CN-101161661-A Method for purifying 2'-hydroxy biphenyl-2-phosphinic acid SHANGHAI CHEMICAL REAGENT RES (CN) 2008-04-16 CN disclosed
EP-1670860-B1 FLAME RETARDANT EPOXY PREPREGS, LAMINATES, AND PRINTED WIRING BOARDS OF ENHANCED THERMAL STABILITY ALBEMARLE CORP (US) 2007-04-04 EP disclosed
CN-1911941-A Preparation method of 2,10-dihydro-9-oxo-10-phospho hetero phenanthrene SHANGHAI CHEMICAL AGENT INST (CN) 2007-02-14 CN disclosed
EP-1670860-A1 FLAME RETARDANT EPOXY PREPREGS, LAMINATES, AND PRINTED WIRING BOARDS OF ENHANCED THERMAL STABILITY ALBEMARLE CORPORATION (US) 2006-06-21 EP disclosed
EP-1657972-A1 Phosphinate complexes of metals of the 2nd, 3rd, 12th and 13th groups and their use as flame proofing agents Schill + Seilacher "Struktol" Aktiengesellschaft (DE) 2006-05-17 EP disclosed
WO-2005040277-A1 FLAME RETARDANT EPOXY PREPREGS, LAMINATES, AND PRINTED WIRING BOARDS OF ENHANCED THERMAL STABILITY ALBEMARLE CORPORATION (US) 2005-05-06 WO disclosed
US-20050075024-A1 Flame retardant epoxy prepregs, laminates, and printed wiring boards of enhanced thermal stability ALBEMARLE CORPORATION 2005-04-07 US disclosed
US-6107506-A Process for producing 2-(2-hydroxyphenyl) phenylphosphinic acid and derivatives SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-08-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100069657-A1 METHOD FOR THE PRODUCTION OF DIBENZ[C,E] [1,2]-OXAPHOSPHORIN DERIVATIVES, AMINO-DIBENZ[C,E] [1,2]-OXAPHOSPHORIN AND ALSO USE THEREOF PFAS, PNP, PNPO ALDH1A1 1291/4885HPGD 1536/4885HSD17B10 3500/4885
US-10913743-B2 Use of organic oxyimides as flame retardant for plastic materials and also flame-retardant plastic material composition and moulded parts produced therefrom ORMDL3, OGDH, FTO ALDH1A1 1554/4885HPGD 827/4885HSD17B10 1318/4885
US-10544284-B2 Use of phosphorous-containing organic oxyimides as flame retardants and/or as stabilizers for plastics, flame-retardant and/or stabilized plastic compositions, method for the production thereof, moulded part, paint and coatings PFAS, FERMT2, PGM2 ALDH1A1 1024/4885HPGD 1530/4885HSD17B10 2172/4885
US-20190263847-A1 METHOD FOR PRODUCING ALKENYL PHOSPHORUS COMPOUND ORC3, OR10J3, ALK ALDH1A1 1631/4885HPGD 2589/4885HSD17B10 1083/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.