Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | AGER | Q15109 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11627488 | 0.80 | HPGD (1.00) | HPGDALDH1A1KMT2APOLBRAB9A | |
| SCHEMBL27680048 | 0.79 | HPGD (0.64) | HPGDALDH1A1KMT2APOLBRAB9A | |
| SCHEMBL21773974 | 0.74 | HPGD (0.52) | HPGDALDH1A1KMT2ALMNAAGER | |
| SCHEMBL21773963 | 0.74 | AGER (0.47) | HPGDKMT2ARAB9AKDM4EHTT | |
| SCHEMBL5321616 | 0.74 | HPGD (0.69) | HPGDALDH1A1KMT2APOLBRAB9A | |
| SCHEMBL14590051 | 0.74 | SMN1; SMN2 (0.65) | HPGDALDH1A1KMT2APOLBRAB9A | |
| SCHEMBL21773973 | 0.74 | MT-CO2 (0.50) | HPGDKMT2ARAB9AKDM4ELMNA | |
| SCHEMBL21773971 | 0.73 | CA1 (0.57) | KMT2ARAB9AHTT | |
| SCHEMBL21773986 | 0.72 | LMNA (0.59) | HPGDKMT2AL3MBTL1LMNA | |
| SCHEMBL3841381 | 0.71 | SMN1; SMN2 (0.69) | HPGDALDH1A1KMT2APOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999677-B2 | Benzylamino-oxoethyl benzamide analogs and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2024-06-04 | — | — | US | disclosed |
| US-20220162157-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2022-05-26 | — | — | US | disclosed |
| US-20200071264-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162157-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | BAD, ATP2A1, IAPP | HPGD 1794/4885ALDH1A1 1776/4885KMT2A 2630/4885 |
| US-20200071264-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | BAD, ATP2A1, IAPP | HPGD 1794/4885ALDH1A1 1776/4885KMT2A 2630/4885 |
| US-11999677-B2 | Benzylamino-oxoethyl benzamide analogs and methods of use | BAD, ATP2A1, IAPP | HPGD 1794/4885ALDH1A1 1776/4885KMT2A 2630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.