Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 12/20 | 0.57 |
| ▸ | CA2 | P00918 | 12/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 6/20 | 0.54 |
| ▸ | CA7 | P43166 | 5/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21773974 | 0.82 | HPGD (0.52) | KMT2A | |
| SCHEMBL21773973 | 0.81 | MT-CO2 (0.50) | CA1CA2RAB9AHTTKMT2A | |
| SCHEMBL21773965 | 0.78 | MT-CO2 (0.53) | KMT2ACYP1A2CYP3A4GAACYP2C19 | |
| SCHEMBL21773986 | 0.75 | LMNA (0.59) | KMT2ACYP1A2CYP3A4GAACYP2C19 | |
| SCHEMBL21773970 | 0.74 | MT-CO2 (0.53) | RAB9AKMT2ACYP1A2GAACYP2C19 | |
| SCHEMBL12407389 | 0.73 | PTGER1 (0.63) | CA1CA2HTTCA12CA7 | |
| SCHEMBL21773994 | 0.73 | HPGD (0.65) | RAB9AHTTKMT2A | |
| SCHEMBL21773963 | 0.73 | AGER (0.47) | RAB9AHTTKMT2AGAA | |
| SCHEMBL31398305 | 0.71 | NLRP3 (0.64) | CA1CA2KMT2ACA12CA7 | |
| SCHEMBL17509993 | 0.71 | CA1 (0.73) | CA1CA2KMT2ACA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999677-B2 | Benzylamino-oxoethyl benzamide analogs and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2024-06-04 | — | — | US | disclosed |
| US-20220162157-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2022-05-26 | — | — | US | disclosed |
| US-20200071264-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162157-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | BAD, ATP2A1, IAPP | CA1 4310/4885CA2 2382/4885RAB9A 1393/4885 |
| US-20200071264-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | BAD, ATP2A1, IAPP | CA1 4310/4885CA2 2382/4885RAB9A 1393/4885 |
| US-11999677-B2 | Benzylamino-oxoethyl benzamide analogs and methods of use | BAD, ATP2A1, IAPP | CA1 4310/4885CA2 2382/4885RAB9A 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.