Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CCR1 | P32246 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MLYCD | O95822 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26625392 | 0.92 | LMNA (0.69) | LMNAHPGDCCR1MEN1PLA2G1B | |
| SCHEMBL21773973 | 0.89 | MT-CO2 (0.50) | LMNAHPGDMEN1KMT2A | |
| SCHEMBL21773965 | 0.77 | MT-CO2 (0.53) | LMNAHPGDMEN1CYP1A2CYP3A4 | |
| SCHEMBL21773974 | 0.76 | HPGD (0.52) | LMNAHPGDMEN1KMT2A | |
| SCHEMBL10389082 | 0.76 | MEN1 (0.70) | LMNAHPGDCCR1MEN1PLA2G1B | |
| SCHEMBL21773971 | 0.75 | CA1 (0.57) | CYP1A2CYP3A4GAACYP2C19KMT2A | |
| SCHEMBL15881788 | 0.74 | L3MBTL1 (0.64) | LMNAHPGDMEN1PLA2G1BCYP1A2 | |
| SCHEMBL4501943 | 0.74 | L3MBTL1 (0.64) | LMNAHPGDMEN1PLA2G1BCYP1A2 | |
| SCHEMBL21773963 | 0.74 | AGER (0.47) | HPGDMEN1GAAKMT2A | |
| SCHEMBL252486 | 0.73 | L3MBTL1 (0.62) | LMNAHPGDMEN1PLA2G1BCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11999677-B2 | Benzylamino-oxoethyl benzamide analogs and methods of use | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) | 2024-06-04 | — | — | US | disclosed |
| US-20220162157-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2022-05-26 | — | — | US | disclosed |
| US-20200071264-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220162157-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | BAD, ATP2A1, IAPP | LMNA 1233/4885HPGD 1794/4885CCR1 4308/4885 |
| US-20200071264-A1 | BENZYLAMINO-OXOETHYL BENZAMIDE ANALOGS AND METHODS OF USE | BAD, ATP2A1, IAPP | LMNA 1233/4885HPGD 1794/4885CCR1 4308/4885 |
| US-11999677-B2 | Benzylamino-oxoethyl benzamide analogs and methods of use | BAD, ATP2A1, IAPP | LMNA 1233/4885HPGD 1794/4885CCR1 4308/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.