Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 10/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | MMP13 | P45452 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14004086 | 0.82 | LMNA (0.59) | CASRHTTIDO1 | |
| SCHEMBL16341200 | 0.79 | ACACB (0.60) | CASRMMP1MMP13HTTF2RL1 | |
| SCHEMBL13996918 | 0.78 | CASR (0.57) | CASRALDH1A1 | |
| SCHEMBL809115 | 0.78 | IDO1 (0.50) | CASRHTTALDH1A1PKMIDO1 | |
| SCHEMBL11132376 | 0.78 | IDO1 (0.50) | CASRHTTALDH1A1PKMIDO1 | |
| Hydrochloric Acid SCHEMBL27494345 | 0.78 | CASR (0.57) | CASR | |
| SCHEMBL73472 | 0.77 | IDO1 (0.54) | ALDH1A1IDO1CALM1 | |
| SCHEMBL8824562 | 0.77 | CASR (0.46) | CASRMMP1MMP13HTTALDH1A1 | |
| SCHEMBL27851489 | 0.76 | LTA4H (0.46) | CASRHTTALDH1A1PKMIDO1 | |
| SCHEMBL26695481 | 0.75 | IDO1 (0.54) | HTTALDH1A1PKMIDO1F2RL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3558954-B1 | IMPROVED PROCESS FOR THE MANUFACTURE OF R-6-HYDROXY-8-[1-HYDROXY-2-[2-(4-METHOXYPHENYL)-1,1-DIMETHYLETHYLAMINOETHYL]-2H-1,4-BENZOXAZIN-3(4H)-ONE HYDROCHLORIDE | INKE SA (ES) | 2021-11-03 | — | — | EP | disclosed |
| US-10800748-B2 | Process for the manufacture of R-6-hydroxy-8-[1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethylethylaminoethyl]-2H-1,4-benzoxazin-3(4H)-one hydrochloride | INKE, S.A. (ES) | 2020-10-13 | — | — | US | disclosed |
| US-20200062723-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF R-6-HYDROXY-8-[1-HYDROXY-2-[2-(4-METHOXYPHENYL)-1,1-DIMETHYLETHYLAMINOETHYL]-2H-1,4-BENZOXAZIN-3(4H)-ONE HYDROCHLORIDE | LABORATORIOS LESVI, S.L. (ES) | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062723-A1 | IMPROVED PROCESS FOR THE MANUFACTURE OF R-6-HYDROXY-8-[1-HYDROXY-2-[2-(4-METHOXYPHENYL)-1,1-DIMETHYLETHYLAMINOETHYL]-2H-1,4-BENZOXAZIN-3(4H)-ONE HYDROCHLORIDE | HTR6, HTR4, HAAO | CASR 559/4885MMP1 3549/4885MMP13 2377/4885 |
| US-10800748-B2 | Process for the manufacture of R-6-hydroxy-8-[1-hydroxy-2-[2-(4-methoxyphenyl)-1,1-dimethylethylaminoethyl]-2H-1,4-benzoxazin-3(4H)-one hydrochloride | HTR6, HTR4, SLC6A6 | CASR 409/4885MMP1 3441/4885MMP13 2812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.