Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23116037 | 0.81 | LOXL2 (0.44) | GABRG2GABRB3GABRA5GABRA3GABRP | |
| SCHEMBL4288596 | 0.78 | PLAU (0.46) | GABRG2GABRB3GABRA5GABRA3GABRP | |
| SCHEMBL30956744 | 0.78 | GABRG2 (0.45) | GABRG2GABRB3GABRA5GABRA3GABRP | |
| SCHEMBL29007904 | 0.78 | ALOX5AP (0.49) | GABRG2GABRB3GABRA5GABRA3GABRP | |
| SCHEMBL16601177 | 0.78 | GABRG2 (0.46) | GABRG2GABRB3GABRA5GABRA3GABRP | |
| SCHEMBL18766867 | 0.78 | L3MBTL1 (0.47) | GABRG2GABRB3GABRA5GABRA3GABRP | |
| SCHEMBL1134458 | 0.75 | HTR2A (0.43) | GABRG2GABRB3GABRA5GABRA3GABRP | |
| SCHEMBL518381 | 0.74 | ALDH1A1 (0.50) | PKMALDH1A1CYP2C19TSHRLMNA | |
| SCHEMBL229009 | 0.74 | GRM5 (0.46) | PKMALDH1A1CYP2C19HDAC6NPC1 | |
| SCHEMBL31219824 | 0.74 | ALDH1A1 (0.50) | PKMALDH1A1CYP2C19TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230137-A1 | PYRAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-07-29 | — | — | US | disclosed |
| US-11001567-B2 | Pyrazine compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-05-11 | — | — | US | disclosed |
| US-20200109128-A1 | PYRAZINE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-04-09 | — | — | US | disclosed |
| US-10577343-B2 | Pyrazine compound and arthropod pest control agent containing same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2020-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230137-A1 | PYRAZINE COMPOUND | PPOX, NOX5, NISCH | GABRG2 3966/4885GABRB3 4609/4885GABRA5 3093/4885 |
| US-10577343-B2 | Pyrazine compound and arthropod pest control agent containing same | PPOX, NOX5, NISCH | GABRG2 3704/4885GABRB3 4461/4885GABRA5 2748/4885 |
| US-11001567-B2 | Pyrazine compound | PPOX, NOX5, NISCH | GABRG2 3966/4885GABRB3 4609/4885GABRA5 3093/4885 |
| US-20200109128-A1 | PYRAZINE COMPOUND | PPOX, NOX5, NISCH | GABRG2 3966/4885GABRB3 4609/4885GABRA5 3093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.