Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | INPPL1 | O15357 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6864378 | 0.86 | CYP1A2 (0.44) | MEN1KMT2ACDK2MAPTKDM4E | |
| SCHEMBL219666 | 0.82 | MAPK1 (0.38) | MEN1KMT2ACDK2MAPTKDM4E | |
| SCHEMBL9689252 | 0.81 | ALDH1A1 (0.37) | MEN1KMT2ACDK2MAPTKDM4E | |
| SCHEMBL6432869 | 0.81 | TSHR (0.40) | MEN1KMT2ACDK2MAPTKDM4E | |
| SCHEMBL10842981 | 0.81 | MAPK1 (0.37) | MEN1KMT2ACDK2MAPTKDM4E | |
| SCHEMBL17205095 | 0.81 | MAPK1 (0.37) | MEN1KMT2ACDK2MAPTKDM4E | |
| SCHEMBL6432865 | 0.79 | DUSP5 (0.47) | MEN1KMT2ACDK2MAPTKDM4E | |
| SCHEMBL13736402 | 0.78 | MAPK1 (0.41) | MEN1KMT2ACDK2MAPTKDM4E | |
| SCHEMBL222715 | 0.76 | CYP1A2 (0.44) | MEN1KMT2ACDK2MAPTKDM4E | |
| SCHEMBL4450226 | 0.71 | ALDH1A1 (0.49) | MEN1KMT2AMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8658795-B2 | Pyridinium boronic acid quenchers for use in analyte sensors | GLUMETRICS, INC. (US) | 2014-02-25 | — | — | US | claimed |
| US-20120208286-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | GLUMETRICS, INC. (US) | 2012-08-16 | — | — | US | claimed |
| EP-2545373-B1 | MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION | MEDTRONIC MINIMED INC (US) | 2022-08-24 | — | — | EP | disclosed |
| EP-2989975-B1 | OPTICAL SYSTEMS AND METHODS FOR RATIONMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | MEDTRONIC MINIMED INC (US) | 2018-06-13 | — | — | EP | disclosed |
| US-9839378-B2 | Optical systems and methods for ratiometric measurement of blood glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2017-12-12 | — | — | US | disclosed |
| US-9757057-B2 | Dry insertion and one-point in vivo calibration of an optical analyte sensor | MEDTRONIC MINIMED, INC. (US) | 2017-09-12 | — | — | US | disclosed |
| US-9693720-B2 | Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement | MEDTRONIC MINIMED, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| EP-2989975-A1 | OPTICAL SYSTEMS AND METHODS FOR RATIONMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | Medtronic MiniMed, Inc. (US) | 2016-03-02 | — | — | EP | disclosed |
| EP-2916722-A1 | DRY INSERTION AND ONE-POINT IN VIVO CALIBRATION OF AN OPTICAL ANALYTE SENSOR | Medtronic MiniMed, Inc. (US) | 2015-09-16 | — | — | EP | disclosed |
| EP-2222686-B1 | POLYVIOLOGEN BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | MEDTRONIC MINIMED INC (US) | 2015-06-17 | — | — | EP | disclosed |
| US-20150080685-A1 | EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT | MEDTRONIC MINIMED, INC. (US) | 2015-03-19 | — | — | US | disclosed |
| US-20060083688-A1 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-04-20 | — | — | US | disclosed |
| US-20040028612-A1 | Optical determination of glucose utilizing boronic acid adducts | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2004-02-12 | — | — | US | disclosed |
| US-6653141-B2 | In vitro detection of polyhydroxyl-substituted organic molecules; obtain sample, incubate in fluorescent dye exposure to excitation light detect and measure signal | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-11-25 | — | — | US | disclosed |
| US-6627177-B2 | Obtaining flurorophore dye which is compatible with the analyte solution; combining withboronic acid-containing quencher molecule; contacting with excitation light source coupled with a detector; producing signal; quantification | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-09-30 | — | — | US | disclosed |
| EP-1340076-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | The Regents of the University of California (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046752-A9 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | UNIV CALIFORNIA (US) | 2002-08-29 | — | — | WO | disclosed |
| US-20020106326-A1 | Polyhydroxyl-substituted organic molecule sensing optical in vivo method utilizing a boronic acid adduct and the device thereof | CALIFORNIA, UNIVERSITY OF THE REGENTS OF THE | 2002-08-08 | — | — | US | disclosed |
| US-20020106810-A1 | Polyhydroxyl-substituted organic molecule sensing optical in vitro method utilizing a boronic acid adduct and the device thereof | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2002-08-08 | — | — | US | disclosed |
| WO-2002046752-A2 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2002-06-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120208286-A1 | PYRIDINIUM BORONIC ACID QUENCHERS FOR USE IN ANALYTE SENSORS | BLVRB, PDXK, PNPO | MEN1 2703/4885KMT2A 3222/4885CDK2 2891/4885 |
| US-20040028612-A1 | Optical determination of glucose utilizing boronic acid adducts | NISCH, BLVRB, FOSB | MEN1 2391/4885KMT2A 3771/4885CDK2 2750/4885 |
| US-20060083688-A1 | Optical determination of glucose utilizing boronic acid adducts | NISCH, FOSB, BLVRB | MEN1 2267/4885KMT2A 3621/4885CDK2 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.