SCHEMBL6432865

SCHEMBL6432865

O=S(=O)([O-])c1c(S(=O)(=O)[O-])c2ccc3cccc4cc(O)c(c1S(=O)(=O)[O-])c2c34.[Na+].[Na+].[Na+]

nearest known ligand 0.47

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 2/20 0.36
DUSP5 Q16690 2/20 0.47
PTPN1 P18031 3/20 0.40
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CDK2 P24941 2/20 0.36
HSD17B10 Q99714 2/20 0.36
APEX1 P27695 2/20 0.36
KDM4E B2RXH2 1/20 0.36
INPPL1 O15357 1/20 0.36
NSD2 O96028 1/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
CYP3A4 P08684 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
PABPC1 P11940 1/20 0.36
PKM P14618 1/20 0.36
IDO1 P14902 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29607184 0.84 DUSP5 (0.41) DUSP5PTPN1THRBMEN1KMT2A
SCHEMBL30241289 0.84 DUSP5 (0.41) DUSP5PTPN1THRBMEN1KMT2A
SCHEMBL2455935 0.84 DUSP5 (0.41) DUSP5PTPN1THRBMEN1KMT2A
SCHEMBL30455688 0.83 ALDH1A1 (0.42) DUSP5PTPN1THRBMEN1KMT2A
SCHEMBL8821685 0.83 ALDH1A1 (0.42) DUSP5PTPN1THRBMEN1KMT2A
SCHEMBL8335873 0.80 DUSP5 (0.37) DUSP5PTPN1THRBMEN1KMT2A
SCHEMBL217795 0.79 MEN1 (0.41) DUSP5THRBMEN1KMT2ACDK2
SCHEMBL219666 0.79 MAPK1 (0.38) DUSP5THRBMEN1KMT2ACDK2
SCHEMBL10842981 0.78 MAPK1 (0.37) DUSP5THRBMEN1KMT2ACDK2
SCHEMBL17205095 0.78 MAPK1 (0.37) DUSP5THRBMEN1KMT2ACDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-61238868-A None JP disclosed
US-12281217-B2 Microstructured film comprising polyalkylene oxide block copolymer, compositions and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-04-22 US disclosed
EP-3662036-B1 WATER SOLUBLE PYRANINE POLYMERS AND METHOD OF MAKING NOURYON CHEMICALS INT BV (NL) 2025-03-26 EP disclosed
CN-114651041-B Microstructured films comprising polyalkylene oxide block copolymers, compositions, and methods 3M创新有限公司 2024-08-30 CN disclosed
US-11859026-B2 Water soluble pyranine polymers and method of making NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2024-01-02 US disclosed
US-20220363877-A1 Microstructured Film Comprising Polyalkylene Oxide Block Copolymer, Compositions and Methods 3M INNOVATIVE PROPERTIES COMPANY 2022-11-17 US disclosed
EP-4061883-A1 MICROSTRUCTURED FILM COMPRISING POLYALKYLENE OXIDE BLOCK COPOLYMER, COMPOSITIONS AND METHODS 3M Innovative Properties Company (US) 2022-09-28 EP disclosed
US-11392899-B2 Managing condensation with angled fluid control features 3M INNOVATIVE PROPERTIES COMPANY (US) 2022-07-19 US disclosed
WO-2021099998-A1 MICROSTRUCTURED FILM COMPRISING POLYALKYLENE OXIDE BLOCK COPOLYMER, COMPOSITIONS AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2021-05-27 WO disclosed
EP-3134691-B1 MANAGING CONDENSATION WITH ANGLED FLUID CONTROL FEATURES 3M INNOVATIVE PROPERTIES CO (US) 2021-04-14 EP disclosed
EP-1005645-A1 OPTICAL CARBON DIOXIDE SENSORS Novartis AG (CH) 2000-06-07 EP disclosed
WO-1999009406-A1 OPTICAL CARBON DIOXIDE SENSORS NOVARTIS AG (CH) 1999-02-25 WO disclosed
EP-0340018-B1 Composition, apparatus and method for sensing ionic components MINNESOTA MINING & MFG (US) 1996-08-14 EP disclosed
EP-0263693-B1 MICRO SENSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-02 EP disclosed
US-4999306-A Composition, apparatus and method for sensing ionic components MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-03-12 US disclosed
US-4886338-A Optical fiber event sensor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-12-12 US disclosed
EP-0340018-A2 Composition, apparatus and method for sensing ionic components MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1989-11-02 EP disclosed
US-4798738-A HYDROPHILIC POLYMER, DYE, OPTICAL FIBER, PH CARDIOVASCULAR DEVICES, INC. (US) 1989-01-17 US disclosed
EP-0263693-A2 Micro sensor MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-04-13 EP disclosed
JP-S61238868-A WATER-BASED STRIPPABLE PAINT COMPOSITION MITSUI TOATSU CHEM INC 1986-10-24 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11859026-B2 Water soluble pyranine polymers and method of making PFAS, NOD1, PARG THRB 3475/4885DUSP5 3544/4885PTPN1 2349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.