Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 7/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21780420 | 0.83 | KMT2A (0.55) | KDM1ASCN9ALMNATSHRGAA | |
| SCHEMBL4247506 | 0.81 | PDE2A (0.50) | KDM1ALMNAGAAALDH1A1HTT | |
| SCHEMBL3662685 | 0.81 | PDE2A (0.50) | KDM1ALMNAGAAALDH1A1HTT | |
| SCHEMBL21780417 | 0.80 | KCNH2 (0.49) | KDM1AKCNH2SCN9ALMNATSHR | |
| SCHEMBL21780440 | 0.78 | LMNA (0.48) | KCNH2SCN9ALMNATSHRGAA | |
| SCHEMBL21780479 | 0.77 | LMNA (0.47) | KCNH2SCN9ALMNATSHRGAA | |
| SCHEMBL21780474 | 0.77 | GPR119 (0.51) | KCNH2SCN9ALMNATSHRKMT2A | |
| SCHEMBL21780441 | 0.77 | LMNA (0.47) | KCNH2SCN9ALMNATSHRGAA | |
| SCHEMBL21780426 | 0.75 | KMT2A (0.53) | SCN9ALMNATSHRGAAALDH1A1 | |
| SCHEMBL5391552 | 0.75 | GAA (0.66) | MCHR1KDM1AKCNH2SCN9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3101013-B1 | FUSED BENZOXAZEPINONES AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2020-10-21 | — | — | EP | disclosed |
| EP-3085696-B1 | FUSED BENZOXAZEPINONES AS ION CHANNEL MODULATORS | GILEAD SCIENCES INC (US) | 2020-03-04 | — | — | EP | disclosed |