Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16370390 | 0.85 | LMNA (0.42) | GAATSHRKMT2ACHRNA7LMNA | |
| SCHEMBL16370388 | 0.85 | LMNA (0.42) | GAATSHRKMT2ACHRNA7LMNA | |
| SCHEMBL15106356 | 0.78 | ALDH1A1 (0.40) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL15106358 | 0.78 | ALDH1A1 (0.40) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL21082485 | 0.77 | GAA (0.45) | GAATSHRKMT2ALMNABCHE | |
| SCHEMBL16370114 | 0.76 | CHRNB2 (0.41) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL20221564 | 0.76 | CHRNB2 (0.41) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL16370113 | 0.76 | CHRNB2 (0.41) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL21782494 | 0.75 | GAA (0.43) | GAATSHRKMT2AMEN1CHRNA7 | |
| SCHEMBL26290154 | 0.75 | ABCB1 (0.46) | GAATSHRBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3682905-B1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | MODERNATX INC (US) | 2021-12-01 | — | — | EP | disclosed |
| EP-3492109-B1 | MODIFIED NUCLEOSIDES, NUCLEOTIDES, AND NUCLEIC ACIDS, AND USES THEREOF | MODERNATX INC (US) | 2020-03-04 | — | — | EP | disclosed |