Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL486788 | 1.00 | HTR6 (0.48) | HTR6DRD1PSIP1ALDH1A1CA1 | |
| SCHEMBL2178308 | 1.00 | HTR6 (0.48) | HTR6DRD1PSIP1ALDH1A1CA1 | |
| SCHEMBL18838428 | 0.80 | CA1 (0.50) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL20082065 | 0.78 | HTR6 (0.46) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL27971051 | 0.78 | ALDH1A1 (0.48) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL15177112 | 0.78 | GAA (0.54) | DRD1ALDH1A1CA1CA2TDP1 | |
| SCHEMBL4280076 | 0.78 | HTR6 (0.46) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL26961003 | 0.78 | HTR6 (0.46) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL24862825 | 0.76 | BRD4 (0.47) | HTR6PSIP1ALDH1A1CA1CA2 | |
| SCHEMBL25315847 | 0.76 | ENPP2 (0.60) | DRD1ALDH1A1CA1CA2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973024-B2 | 24-sulfoximine vitamin D3 compounds | Cyctochroma Inc. (CA) | 2011-07-05 | — | — | US | disclosed |
| US-20060217353-A1 | 24-sulfoximine vitamin D3 compounds | CYTOCHROMA INC. (CA) | 2006-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060217353-A1 | 24-sulfoximine vitamin D3 compounds | CYP24A1, CYP2R1, CYP27B1 | HTR6 2945/4885DRD1 558/4885PSIP1 1472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.