Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20059897 | 0.87 | ALDH1A1 (0.43) | ALDH1A1TDP1MAPTPOLBKDM4E | |
| SCHEMBL21089427 | 0.78 | POLB (0.41) | ALDH1A1TDP1MAPTPOLBKDM4E | |
| SCHEMBL8083467 | 0.77 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPTPOLBKDM4E | |
| SCHEMBL27182104 | 0.75 | MEN1 (0.40) | ALDH1A1TDP1MAPTPOLBKDM4E | |
| SCHEMBL4198877 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TDP1MAPTPOLBKDM4E | |
| SCHEMBL13191817 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TDP1MAPTPOLBKDM4E | |
| SCHEMBL22328111 | 0.74 | TDP1 (0.41) | ALDH1A1TDP1MAPTPOLBKDM4E | |
| SCHEMBL11611662 | 0.74 | LMNA (0.38) | ALDH1A1TDP1MAPTPOLBKDM4E | |
| SCHEMBL7323969 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPTPOLBKDM4E | |
| SCHEMBL7323961 | 0.73 | ALDH1A1 (0.48) | ALDH1A1TDP1MAPTPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4010352-B1 | A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES | GYROS PROTEIN TECH AB (SE) | 2023-10-18 | — | — | EP | disclosed |
| EP-4219446-A2 | TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION | Gyros Protein Technologies AB (SE) | 2023-08-02 | — | — | EP | disclosed |
| WO-2023060858-A1 | MONOCHROMATIC FLUORESCENCE MRT GENE SEQUENCING REAGENT AND METHOD BASED ON ENVIRONMENT-SENSITIVE DYE | 深圳铭毅智造科技有限公司 | 2023-04-20 | — | — | WO | disclosed |
| US-20220211883-A1 | FAP-ACTIVATED RADIOTHERANOSTICS AND USES RELATED THERETO | TRUSTEES OF TUFTS COLLEGE | 2022-07-07 | — | — | US | disclosed |
| US-20210332082-A1 | TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION | Belyntic GmbH (DE) | 2021-10-28 | — | — | US | disclosed |
| WO-2021023892-A1 | A METHOD FOR MODIFICATION OF PEPTIDES IMMOBILIZED ON A SOLID SUPPORT BY TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES | Belyntic GmbH (DE) | 2021-02-11 | — | — | WO | disclosed |
| WO-2020043747-A1 | TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION | Belyntic GmbH (DE) | 2020-03-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332082-A1 | TRACELESS REDUCTIVELY CLEAVABLE LINKER MOLECULES FOR PEPTIDE PURIFICATION | VIP, NGLY1, HM13 | ALDH1A1 1635/4885TDP1 3829/4885MAPT 1722/4885 |
| US-20220211883-A1 | FAP-ACTIVATED RADIOTHERANOSTICS AND USES RELATED THERETO | FAP, FIBP, FGFR1 | ALDH1A1 789/4885TDP1 283/4885MAPT 3059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.