SCHEMBL21787616

SCHEMBL21787616

Cc1ccc2c(N)c(Cc3cc(Cl)c4nc(C)ccc4c3N)cc(Cl)c2n1

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
NR4A2 P43354 3/20 0.44
KDM4E B2RXH2 5/20 0.39
HTT P42858 3/20 0.39
PKM P14618 1/20 0.39
KMT2A Q03164 4/20 0.37
ADORA1 P30542 2/20 0.37
ADORA2A P29274 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CCR1 P32246 1/20 0.35
RAB9A P51151 1/20 0.35
CCR5 P51681 1/20 0.35
GAA P10253 1/20 0.35
TSHR P16473 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
ALDH1A1 P00352 2/20 0.34
OPRK1 P41145 1/20 0.34
S1PR4 O95977 1/20 0.34
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21787582 0.75 ALDH1A1 (0.44) MAPTKDM4EHTTPKMKMT2A
SCHEMBL4738026 0.74 MAPT (0.66) MAPTNR4A2KDM4EHTTPKM
SCHEMBL11557724 0.70 NR4A2 (0.59) MAPTNR4A2KDM4EHTTPKM
SCHEMBL21787707 0.69 KDM4E (0.43) NR4A2KDM4EKMT2AADORA1ADORA2A
SCHEMBL20838482 0.68 MAPT (0.49) MAPTNR4A2KDM4EHTTPKM
SCHEMBL20838492 0.67 CCR1 (0.58) MAPTNR4A2KDM4EKMT2AL3MBTL1
SCHEMBL10698909 0.67 KDM4E (0.48) MAPTNR4A2KDM4EHTTPKM
SCHEMBL10697698 0.67 MAPT (0.51) MAPTNR4A2KDM4EHTTPKM
SCHEMBL24207472 0.66 CCR1 (0.40) MAPTNR4A2KDM4EKMT2AADORA1
SCHEMBL21787615 0.66 CCR1 (0.45) MAPTNR4A2KDM4EHTTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021117410-A1 QUINOPHTHALONE COMPOUND, PIGMENT COMPOSITION, AND COLOR FILTER DIC株式会社 2021-06-17 WO disclosed
US-20200239693-A1 QUINOPHTHALONE COMPOUND DIC CORPORATION (JP) 2020-07-30 US disclosed
WO-2020045200-A1 ALKYLENE COMPOUND, QUINOPHTHALONE COMPOUND, AND QUINOPHTHALONE MIXTURE DIC株式会社 2020-03-05 WO disclosed
WO-2020045197-A1 PIGMENT COMPOSITION, COLORING COMPOSITION AND COLOR FILTER DIC株式会社 2020-03-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200239693-A1 QUINOPHTHALONE COMPOUND TYR, NDUFS6, NDUFA6 MAPT 3243/4885NR4A2 1551/4885KDM4E 3806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.