SCHEMBL217886

SCHEMBL217886

Cc1c(C)c(CO)c(C)c(CO)c1C

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL357717 0.96 KDM4E (0.32) KDM4EALDH1A1HPGDHSD17B10GABRA1
SCHEMBL4175469 0.93 KDM4E (0.33) KDM4EALDH1A1HPGDHSD17B10GABRA1
SCHEMBL217789 0.93 KDM4E (0.33) KDM4EALDH1A1HPGDHSD17B10GABRA1
SCHEMBL10598219 0.89 KDM4E (0.32) KDM4EALDH1A1HPGDHSD17B10GABRA1
SCHEMBL12766214 0.85 KDM4E (0.33) KDM4EALDH1A1HPGDHSD17B10GABRA1
SCHEMBL8351615 0.82 KDM4E (0.35) KDM4EALDH1A1HPGDHSD17B10GABRA1
SCHEMBL13199170 0.81 KDM4E (0.32) KDM4EALDH1A1HPGDHSD17B10GABRA1
SCHEMBL12766210 0.81 KDM4E (0.32) KDM4EALDH1A1HPGDHSD17B10GABRA1
SCHEMBL2798558 0.80 KDM4E (0.38) KDM4EALDH1A1HPGDHSD17B10GABRA1
SCHEMBL5516684 0.80 KDM4E (0.38) KDM4EALDH1A1HPGDHSD17B10GABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106398722-B Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2018-11-02 CN disclosed
CN-106398722-A Liquid crystal alignment agent, liquid crystal alignment film and liquid crystal display element 奇美实业股份有限公司 2017-02-15 CN disclosed
US-8088548-B2 Bottom antireflective coating compositions AZ ELECTRONIC MATERIALS USA CORP. (US) 2012-01-03 US disclosed
WO-2011120002-A1 THERMAL-RESPONSIVE POLYMER NETWORKS, COMPOSITIONS, AND METHODS AND APPLICATIONS RELATED THERETO UNIVERSITY OF MASSACHUSETTS (US) 2011-09-29 WO disclosed
EP-2212273-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ Electronic Materials USA Corp. (US) 2010-08-04 EP disclosed
WO-2009053832-A2 BOTTOM ANTIREFLECTIVE COATING COMPOSITIONS AZ ELECTRONIC MATERIALS USA CORP. (DE) 2009-04-30 WO disclosed
US-20090104559-A1 Bottom Antireflective Coating Compositions MERCK PATENT GMBH (DE) 2009-04-23 US disclosed
US-20060063105-A1 Negative-working photoimageable bottom antireflective coating OBERLANDER JOSEPH E 2006-03-23 US disclosed
US-6830804-B2 Reacting an acid-terminated unsaturated polyetherester resin with an aromatic polyol; nonblistering fiber-reinforced polymers COOK COMPOSITES AND POLYMERS CO. 2004-12-14 US disclosed
EP-1466215-A1 NEGATIVE DEEP ULTRAVIOLET PHOTORESIST Clariant International Ltd. (CH) 2004-10-13 EP disclosed
EP-1219583-B1 Process for producing bromo-aromatic condensed ring compound SUMITOMO CHEMICAL CO (JP) 2004-02-25 EP disclosed
US-20030215736-A1 Negative-working photoimageable bottom antireflective coating AZ ELECTRONIC MATERIALS USA CORP. 2003-11-20 US disclosed
WO-2003058347-A1 NEGATIVE DEEP ULTRAVIOLET PHOTORESIST CLARIANT INTERNATIONAL LTD (CH) 2003-07-17 WO disclosed
WO-2003058345-A2 NEGATIVE-WORKING PHOTOIMAGEABLE BOTTOM ANTIREFLECTIVE COATING CLARIANT INTERNATIONAL LTD (CH) 2003-07-17 WO disclosed
US-20030129527-A1 Negative deep ultraviolet photoresist AZ ELECTRONIC MATERIALS USA CORP. 2003-07-10 US disclosed
EP-1219583-A1 Process for producing bromo-aromatic condensed ring compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-07-03 EP disclosed
US-20020055597-A1 Aromatic polyol end-capped unsaturated polyetherester resins and resin compositions containing the same having improved chemical and/or water resistance HSU CHIH-PIN (US) 2002-05-09 US disclosed
US-6211305-B1 CURABLE THERMOSETTING RESIN COOK COMPOSITES AND POLYMERS CO. 2001-04-03 US disclosed
EP-0930327-A2 Aromatic polyol end-capped unsaturated polyetherester resins and resin compositions containing the same having improved chemical and/or water resistance Cook Composites and Polymers Company (US) 1999-07-21 EP disclosed
EP-0543761-A1 Crosslinkable aqueous developable photoresist compositions and method for use thereof International Business Machines Corporation (US) 1993-05-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090104559-A1 Bottom Antireflective Coating Compositions SDC2, S100A9, MYH9 KDM4E 934/4885ALDH1A1 3154/4885HPGD 4856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.