Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12403860 | 0.79 | RAPGEF4 (0.42) | RAPGEF4RIPK1 | |
| SCHEMBL21790579 | 0.75 | TDO2 (0.34) | RAPGEF4 | |
| SCHEMBL21790748 | 0.75 | TAS1R3 (0.40) | — | |
| SCHEMBL23084860 | 0.74 | KDM4E (0.38) | — | |
| SCHEMBL21790791 | 0.73 | MEN1 (0.42) | RAPGEF4 | |
| SCHEMBL21790800 | 0.72 | KMT2A (0.43) | — | |
| SCHEMBL24979193 | 0.70 | AR (0.32) | — | |
| SCHEMBL20332825 | 0.69 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL1453847 | 0.69 | GAA (0.43) | — | |
| SCHEMBL21790802 | 0.69 | PTGS2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | ESANEX INC (US) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200071308-A1 | Benzene, Pyridine, and Pyridazine Derivatives | CDK4, P2RX4, MKI67 | RAPGEF4 3156/4885RIPK1 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.