SCHEMBL21790454

SCHEMBL21790454

COOP(=O)(C(=O)c1c(C)cc(C)cc1C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.36
LMNA P02545 3/20 0.35
KMT2A Q03164 8/20 0.35
MEN1 O00255 7/20 0.35
SMN1; SMN2 Q16637 3/20 0.33
HPGD P15428 1/20 0.33
ABCB1 P08183 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
CFTR P13569 1/20 0.33
ATM Q13315 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL710803 0.88 POLB (0.38) POLBLMNAKMT2AMEN1SMN1; SMN2
SCHEMBL25188744 0.85 MEN1 (0.40) POLBLMNAKMT2AMEN1SMN1; SMN2
SCHEMBL22172022 0.84 ABCB1 (0.36) POLBLMNAKMT2AMEN1SMN1; SMN2
SCHEMBL713632 0.82 HPGD (0.43) LMNAKMT2AMEN1HPGD
SCHEMBL8938989 0.82 KMT2A (0.37) POLBLMNAKMT2AMEN1SMN1; SMN2
Methoxymethane SCHEMBL29366991 0.82 POLB (0.38) POLBLMNAKMT2AMEN1SMN1; SMN2
SCHEMBL7622714 0.82 CA2 (0.48) POLBLMNAKMT2AMEN1SMN1; SMN2
SCHEMBL36028 0.81 LMNA (0.48) POLBLMNAKMT2AMEN1SMN1; SMN2
SCHEMBL155284 0.81 ALDH1A1 (0.46) POLBLMNAKMT2AMEN1SMN1; SMN2
SCHEMBL8938991 0.81 PKM (0.43) POLBLMNAHPGDMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11036135-B2 Curable composition, cured product thereof, and curing method therefor ADEKA CORPORATION (JP) 2021-06-15 US disclosed
US-20200073239-A1 CURABLE COMPOSITION, CURED PRODUCT THEREOF, AND CURING METHOD THEREFOR ADEKA CORPORATION (JP) 2020-03-05 US disclosed