Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.54 |
| ▸ | ACLY | P53396 | 2/20 | 0.52 |
| ▸ | ACACA | Q13085 | 2/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.48 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLA1 | P09884 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13358790 | 0.90 | ACLY (0.63) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL13801861 | 0.90 | ACLY (0.63) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL982765 | 0.90 | ACLY (0.63) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL1878721 | 0.90 | ACLY (0.63) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL14520017 | 0.90 | ACLY (0.63) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL14047057 | 0.90 | ACLY (0.63) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL12152345 | 0.90 | ACLY (0.63) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL13420256 | 0.90 | ACLY (0.63) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL1878720 | 0.90 | ACLY (0.63) | HSD11B1ACLYACACAPTPN11HSD11B2 | |
| SCHEMBL11408854 | 0.90 | ACLY (0.63) | HSD11B1ACLYACACAPTPN11HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210315960-A1 | COMPOSITIONS OF AZADIRACHTA INDICA AND METHODS OF TREATING CANCER | SOMAN GIRISH SUDHAKAR (IN) | 2021-10-14 | — | — | US | disclosed |
| US-20200069636-A1 | PROCESS FOR PREPARATION OF CO2 EXTRACT OF AZADIRACHTA INDICA AND HERBAL COMPOSITIONS THEREOF FOR TREATMENT OF CANCERS | NISARGA BIOTECH PRIVATE LIMITED (IN) | 2020-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200069636-A1 | PROCESS FOR PREPARATION OF CO2 EXTRACT OF AZADIRACHTA INDICA AND HERBAL COMPOSITIONS THEREOF FOR TREATMENT OF CANCERS | SCO2, SI, CYP1A2 | HSD11B1 1578/4885ACLY 380/4885ACACA 1164/4885 |
| US-20210315960-A1 | COMPOSITIONS OF AZADIRACHTA INDICA AND METHODS OF TREATING CANCER | SCO2, NOC2L, NPM1 | HSD11B1 2785/4885ACLY 732/4885ACACA 1750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.